Development of a tool to calculate the probability of hypocalcemia after total thyroidectomy: a prospective study

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorSoares, Carlos Segundo Paiva-
Autor(es): dc.creatorKoga, Katia Hiromoto-
Autor(es): dc.creatorMoriguchi, Sonia Marta-
Autor(es): dc.creatorTerra, Simone Antunes-
Autor(es): dc.creatorTagliarini, José Vicente-
Autor(es): dc.creatorde Vasconcelos Affonso, Pedro Henrique Dalmolin-
Autor(es): dc.creatorda Silva Pechutti, Monise-
Autor(es): dc.creatorda Silva Mazeto, Gláucia Maria Ferreira-
Data de aceite: dc.date.accessioned2025-08-21T17:16:22Z-
Data de disponibilização: dc.date.available2025-08-21T17:16:22Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s00423-024-03229-8-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/299411-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/299411-
Descrição: dc.descriptionPurpose: This study aimed to evaluate the ability of the percentage of decrease in serum PTH level in the first 8 h after total thyroidectomy (TT) to predict hypocalcemia requiring Ca supplementation and develop a tool to predict it. Methods: 97 patients who underwent TT with measurement of preoperative parathyroid hormone (PTH) levels were prospectively evaluated 1 and 8 h after TT; postoperative magnesium (Mg2PO) and phosphorus levels were evaluated on the 2nd day after surgery. The percentage of decrease in PTH level 1 h (%dPTH1h) and 8 h (%dPTH8h) postoperatively and predictors of hypocalcemia requiring Ca supplementation were evaluated and an equation was developed to predict this outcome. Results: %dPTH1h (p = 0.002), %dPTH8h (p = 0.001) and (Mg2PO) (p < 0.01) were isolated predictors of postoperative hypocalcemia requiring Ca supplementation. The data obtained led to the development of two tools to predict this complication. Conclusions: The percentage of decrease in PTH level 1 h and 8 h postoperatively and the magnesium level on the 2nd day after surgery were predictors of more severe hypocalcemia, and an auxiliary tool for predicting this complication was developed.-
Descrição: dc.descriptionDepartment of Surgical Specialties and Anesthesiology Botucatu Medical School Sao Paulo State University – Unesp, SP-
Descrição: dc.descriptionDepartment of Surgical Specialties and Anesthesiology, Av. Professor Mário Rubens Guimarães Montenegro, s/n, UNESP Campus de Botucatu, SP-
Descrição: dc.descriptionNuclear Medicine Department Botucatu Medical School Sao Paulo State University – Unesp, SP-
Descrição: dc.descriptionPathology Department Botucatu Medical School Sao Paulo State University – Unesp, SP-
Descrição: dc.descriptionBotucatu Medical School Sao Paulo State University – Unesp, SP-
Descrição: dc.descriptionInternal Medicine Department Botucatu Medical School Sao Paulo State University – Unesp, SP-
Descrição: dc.descriptionDepartment of Surgical Specialties and Anesthesiology Botucatu Medical School Sao Paulo State University – Unesp, SP-
Descrição: dc.descriptionNuclear Medicine Department Botucatu Medical School Sao Paulo State University – Unesp, SP-
Descrição: dc.descriptionPathology Department Botucatu Medical School Sao Paulo State University – Unesp, SP-
Descrição: dc.descriptionBotucatu Medical School Sao Paulo State University – Unesp, SP-
Descrição: dc.descriptionInternal Medicine Department Botucatu Medical School Sao Paulo State University – Unesp, SP-
Idioma: dc.languageen-
Relação: dc.relationLangenbeck's Archives of Surgery-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectHypocalcemia-
Palavras-chave: dc.subjectMagnesium-
Palavras-chave: dc.subjectParathyroid hormone-
Palavras-chave: dc.subjectPhosphorus-
Palavras-chave: dc.subjectThyroidectomy-
Título: dc.titleDevelopment of a tool to calculate the probability of hypocalcemia after total thyroidectomy: a prospective study-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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