Multifocal Necrotizing Sialometaplasia in the Tongue Surgical Specimen: An Immunohistochemical Study

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.creatorMarques, Marcelo Borges-
Autor(es): dc.creatorPosantes, Gabriela Esperanza Maradiaga-
Autor(es): dc.creatorGonçalves, Luana Stefanie Silvino-
Autor(es): dc.creatorda Silva, Anderson Tangerino Ferreira-
Autor(es): dc.creatorSilveira, Heitor Albergoni-
Autor(es): dc.creatorChahud, Fernando-
Autor(es): dc.creatorLeón, Jorge Esquiche-
Data de aceite: dc.date.accessioned2025-08-21T17:14:10Z-
Data de disponibilização: dc.date.available2025-08-21T17:14:10Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2025-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s12105-025-01756-4-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/299200-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/299200-
Descrição: dc.descriptionBackground: Necrotizing sialometaplasia (NSM) is a rare self-limiting inflammatory lesion, with most cases affecting the minor salivary glands, especially those located in the palate (70%). To date, about 261 cases of NSM have been reported. Of them, 7 cases affected the tongue; 37 cases occurred after surgery; and 17 cases showed association with neoplasms. Methods: A 50-year-old male patient was diagnosed with squamous cell carcinoma (SCC) of the tongue. After surgical excision, the tumor diagnosis was well-differentiated SCC with a close surgical margin. Re-excision of the margin was indicated. Results: Microscopically, the surgical margin showed neither residual SCC nor epithelial dysplasia. However, it was possible to observe 7 foci containing typical areas of NSM distributed throughout the surgical specimen, which, by immunohistochemistry, revealed a glandular nature with presence of myoepithelial cells. Conclusion: We present here an unusual multifocal NSM affecting the tongue at the site of a prior resection for SCC with close margins, which, to the best of our knowledge, has not been reported to date.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionOral Medicine Department of Diagnosis and Surgery Araraquara Dental School FOAr/UNESP-
Descrição: dc.descriptionOral Pathology Department of Stomatology Public Oral Health and Forensic Dentistry Ribeirão Preto Dental School (FORP/USP) University of São Paulo-
Descrição: dc.descriptionDepartment of Pathology and Forensic Medicine Ribeirão Preto Medical School (FMRP/ USP) University of São Paulo-
Descrição: dc.descriptionOral Medicine Department of Diagnosis and Surgery Araraquara Dental School FOAr/UNESP-
Descrição: dc.descriptionCAPES: 001-
Descrição: dc.descriptionFAPESP: 2016/11419-0; 2022/07479-9-
Descrição: dc.descriptionFAPESP: 2022/12760-9-
Descrição: dc.descriptionCNPq: 304241/2021-0-
Idioma: dc.languageen-
Relação: dc.relationHead and Neck Pathology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectDifferential diagnosis-
Palavras-chave: dc.subjectImmunohistochemistry-
Palavras-chave: dc.subjectNecrotizing sialometaplasia-
Palavras-chave: dc.subjectOral cavity-
Palavras-chave: dc.subjectSquamous cell carcinoma-
Título: dc.titleMultifocal Necrotizing Sialometaplasia in the Tongue Surgical Specimen: An Immunohistochemical Study-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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