Insights into enterovirus a-71 antiviral development: from natural sources to synthetic nanoparticles

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Federal de Uberlândia (UFU)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorFaculty of Medicine of Sao Jose do Rio Preto-
Autor(es): dc.creatorFeferbaum-Leite, Shiraz-
Autor(es): dc.creatorSantos, Igor Andrade-
Autor(es): dc.creatorGrosche, Victória Riquena-
Autor(es): dc.creatorda Silva, Gislaine Celestino Dutra-
Autor(es): dc.creatorJardim, Ana Carolina Gomes-
Data de aceite: dc.date.accessioned2025-08-21T16:25:46Z-
Data de disponibilização: dc.date.available2025-08-21T16:25:46Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2023-10-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s00203-023-03660-3-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/299050-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/299050-
Descrição: dc.descriptionEnteroviruses are pathogens responsible for several diseases, being enterovirus A71 (EVA71) the second leading cause of hand, foot, and mouth disease (HFMD), especially in Asia–Pacific countries. HFMD is mostly common in infants and children, with mild symptoms. However, the disease can result in severe nervous system disorders in children as well as in immunosuppressed adults. The virus is highly contagious, and its transmission occurs via fecal–oral, oropharyngeal secretions, and fomites. The EVA71 burdens the healthy systems and economies around the world, however, up to date, there is no antiviral approved to treat infected individuals and the existent vaccines are not available or approved to be used worldwide. In this context, an extensive literature research was conducted to describe and summarize the recent advances in natural and/or synthetic compounds with antiviral activity against EVA71. The summarized data presented here might simply encourage the future studies in EVA71 antiviral development, by encouraging further research encompassing these compounds or even the application of the techniques and technologies to improve or produce new antiviral molecules.-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG)-
Descrição: dc.descriptionInstitute of Biomedical Science (ICBIM) Federal University of Uberlandia (UFU), Minas Gerais-
Descrição: dc.descriptionSao Paulo State University, Sao Jose do Rio Preto-
Descrição: dc.descriptionFaculty of Medicine of Sao Jose do Rio Preto-
Descrição: dc.descriptionSao Paulo State University, Sao Jose do Rio Preto-
Descrição: dc.descriptionCNPq: 142495/2020–4-
Descrição: dc.descriptionCAPES: 88887.505971/2020–00-
Descrição: dc.descriptionCAPES: 88887.703841/2022-00-
Descrição: dc.descriptionFAPEMIG: APQ-01487-22-
Idioma: dc.languageen-
Relação: dc.relationArchives of Microbiology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAntivirals-
Palavras-chave: dc.subjectEnterovirus A-71-
Palavras-chave: dc.subjectHFMD-
Palavras-chave: dc.subjectNatural and synthetic compounds-
Título: dc.titleInsights into enterovirus a-71 antiviral development: from natural sources to synthetic nanoparticles-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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