Placental mitochondrial impairment and its association with maternal metabolic dysfunction

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorSchool of Medicine and Health Sciences-
Autor(es): dc.contributorPontificia Universidad Católica de Chile-
Autor(es): dc.contributorUniversity Medical Center Groningen-
Autor(es): dc.contributorUniversidad de Sevilla-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversity of Queensland-
Autor(es): dc.creatorGrismaldo R, Adriana-
Autor(es): dc.creatorLuévano-Martínez, Luis A.-
Autor(es): dc.creatorReyes, Monserrat-
Autor(es): dc.creatorGarcía-Márquez, Grecia-
Autor(es): dc.creatorGarcía-Rivas, Gerardo-
Autor(es): dc.creatorSobrevia, Luis-
Data de aceite: dc.date.accessioned2025-08-21T17:21:28Z-
Data de disponibilização: dc.date.available2025-08-21T17:21:28Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2023-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1113/JP285935-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/298778-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/298778-
Descrição: dc.descriptionThe placenta plays an essential role in pregnancy, leading to proper fetal development and growth. As an organ with multiple physiological functions for both mother and fetus, it is a highly energetic and metabolically demanding tissue. Mitochondrial physiology plays a crucial role in the metabolism of this organ and thus any alteration leading to mitochondrial dysfunction has a severe outcome in the development of the fetus. Pregnancy-related pathological states with a mitochondrial dysfunction outcome include preeclampsia and gestational diabetes mellitus. In this review, we address the role of mitochondrial morphology, metabolism and physiology of the placenta during pregnancy, highlighting the roles of the cytotrophoblast and syncytiotrophoblast. We also describe the relationship between preeclampsia, gestational diabetes, gestational diabesity and pre-pregnancy maternal obesity with mitochondrial dysfunction. (Figure presented.).-
Descrição: dc.descriptionTecnologico de Monterrey Institute for Obesity Research School of Medicine and Health Sciences, Nuevo León-
Descrição: dc.descriptionCellular and Molecular Physiology Laboratory (CMPL) Department of Obstetrics Division of Obstetrics and Gynaecology School of Medicine Faculty of Medicine Pontificia Universidad Católica de Chile-
Descrição: dc.descriptionDepartment of Pathology and Medical Biology University of Groningen University Medical Center Groningen-
Descrição: dc.descriptionDepartment of Physiology Faculty of Pharmacy Universidad de Sevilla-
Descrição: dc.descriptionMedical School (Faculty of Medicine) São Paulo State University (UNESP)-
Descrição: dc.descriptionUniversity of Queensland Centre for Clinical Research (UQCCR) Faculty of Medicine and Biomedical Sciences University of Queensland-
Descrição: dc.descriptionMedical School (Faculty of Medicine) São Paulo State University (UNESP)-
Idioma: dc.languageen-
Relação: dc.relationJournal of Physiology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectgestational diabetes-
Palavras-chave: dc.subjectmetabolic dysfunction-
Palavras-chave: dc.subjectmitochondria-
Palavras-chave: dc.subjectobesity-
Palavras-chave: dc.subjectplacenta-
Palavras-chave: dc.subjectpreeclampsia-
Palavras-chave: dc.subjectpregnancy-
Título: dc.titlePlacental mitochondrial impairment and its association with maternal metabolic dysfunction-
Tipo de arquivo: dc.typevídeo-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.