Dynamical Metabolic Model for Optimizing Biotin-Regulated Lipid Production in Microalgae-Bacteria Symbiosis

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversité Côte d'Azur-
Autor(es): dc.contributorStation Zoologique-
Autor(es): dc.creatorPessi, Bruno Assis-
Autor(es): dc.creatorBernard, Olivier-
Data de aceite: dc.date.accessioned2025-08-21T23:19:27Z-
Data de disponibilização: dc.date.available2025-08-21T23:19:27Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-07-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.ifacol.2024.08.329-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/298380-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/298380-
Descrição: dc.descriptionExploiting natural symbioses to enhance productivity of bioprocesses is an emerging trend. For optimizing such complex associations of microorganisms, a model of symbiotic interactions is vital. This challenging task has attracted much attention. Here, a reduced metabolic model describing a symbiotic interaction between bacteria E. coli, overproducing vitamin biotin (B7), and microalgae Chlorella is developed. The symbiosis involves B7 exchange, impacting lipid synthesis regulation in microalgae. Our model shows a trade-off between light availability and biotin production, leading to an optimization problem for lipid production. We numerically determine the optimal conditions, demonstrating the feasibility of this strategy to enhance microalgae cultivation.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionAdvanced Research Projects Agency-
Descrição: dc.descriptionHigher Education Discipline Innovation Project-
Descrição: dc.descriptionSchool of Engineering Bauru Department of Civil and Environmental Engineering São Paulo State University (UNESP)-
Descrição: dc.descriptionBIOCORE INRIA Université Côte d'Azur, BP 93-
Descrição: dc.descriptionLOV Sorbonne University CNRS UMR 7093 Station Zoologique, BP 28-
Descrição: dc.descriptionSchool of Engineering Bauru Department of Civil and Environmental Engineering São Paulo State University (UNESP)-
Descrição: dc.descriptionAdvanced Research Projects Agency: ANR-15-IDEX-0001-
Descrição: dc.descriptionHigher Education Discipline Innovation Project: ANR-20-CE45-0014-
Formato: dc.format151-156-
Idioma: dc.languageen-
Relação: dc.relationIFAC-PapersOnLine-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBioprocess control-
Palavras-chave: dc.subjectMetabolic engineering-
Palavras-chave: dc.subjectMicroalgae-
Palavras-chave: dc.subjectMicrobial technology-
Palavras-chave: dc.subjectModel reduction-
Palavras-chave: dc.subjectOptimization-
Título: dc.titleDynamical Metabolic Model for Optimizing Biotin-Regulated Lipid Production in Microalgae-Bacteria Symbiosis-
Tipo de arquivo: dc.typeaula digital-
Aparece nas coleções:Repositório Institucional - Unesp

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