Prevalence and antibiotic resistance in bacterial isolates of dogs with ulcerative keratitis in São Paulo State, Brazil

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade Estadual de Maringá (UEM)-
Autor(es): dc.contributorBiological Institute-
Autor(es): dc.contributorIndependent Statistical Analyst-
Autor(es): dc.creatorCasemiro, Pamella A. F.-
Autor(es): dc.creatorAndrade, Alexandre L.-
Autor(es): dc.creatorCardozo, Marita V.-
Autor(es): dc.creatorRodrigues, Romário A.-
Autor(es): dc.creatorSilva, Jaqueline A.-
Autor(es): dc.creatorMarinho, Márcia-
Autor(es): dc.creatorNassar, Alessandra F. C.-
Autor(es): dc.creatorCastro, Vanessa-
Autor(es): dc.creatorBraz, Guilherme H. R.-
Autor(es): dc.creatorGujanwski, Cinthya A.-
Autor(es): dc.creatorPadua, Ivan R. M.-
Autor(es): dc.creatorMoraes, Paola C.-
Data de aceite: dc.date.accessioned2025-08-21T18:01:11Z-
Data de disponibilização: dc.date.available2025-08-21T18:01:11Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1111/vop.13224-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/298181-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/298181-
Descrição: dc.descriptionObjective: Identify microorganisms present in canine eyes affected by ulcerative keratitis and assess its resistance profile to available antimicrobial drugs. Methods: Samples were collected from 88 canine eyes that exhibited ulcerative keratitis. They were identified using MALDI-TOF and subjected to antimicrobial susceptibility testing by disk diffusion. Results: Among the assessed subjects, brachycephalic dogs accounted for 74.48% (50/83) of the evaluated canines. Among the 88 evaluated eyes, 90.9% (80/88) showed positive cultures, with 11.33% (10/88) of the samples isolating more than one species of bacteria. Of all bacterial isolates identified (90), Gram-positive bacteria accounted for 63.33% (57/90), while Gram-negative bacteria constituted 36.66% (33/90), with predominance of Staphylococcus spp. at 35.55% (32/90) being, Staphylococcus pseudintermedius at 68.75% (22/32), and Pseudomonas aeruginosa at 15.55% (14/90), respectively. Staphylococcus spp. exhibited resistance to penicillin (89.29%), sulfadiazine and trimethoprim (60.71%), and tetracycline (67.86%), while doxycycline (88.89%), cefotaxime (85.71%), chloramphenicol (82.14%), gentamicin, and moxifloxacin (78.57%) showed the highest sensitivity rates. Pseudomonas aeruginosa displayed sensitivity (100%) to gentamicin and imipenem, and resistance (8.33%) to norfloxacin, ciprofloxacin, and cefepime. Similarly, the Enterobacteriaceae family showed higher sensitivity to amikacin and gentamicin (88.89%), imipenem (88.24%), and levofloxacin (87.5%), with pronounced resistance to amoxicillin-clavulanate (50%) and cefazolin (47.06%). This highlights multiresistance in 23.33% (21/90) of the isolates. Conclusions: The most isolated species in canine ulcerative keratitis are S. pseudintermedius and P. aeruginosa. However, other species were also isolated, demonstrating diversity in ocular microbiota infection. There is a high-rate multidrug resistance associated with canine ulcerative keratitis. Nevertheless, these strains exhibited sensitivity to antimicrobials commonly used in veterinary ophthalmology.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionDepartment of Veterinary Clinical and Surgical Sciences FCAV UNESP-
Descrição: dc.descriptionDepartment of Veterinary Clinical Surgery and Animal Reproduction Animal FMVA-UNESP-
Descrição: dc.descriptionDepartment of Biomedical Sciences and Health UEMG-
Descrição: dc.descriptionDepartment of Pathology Reproduction and One Health FCAV UNESP-
Descrição: dc.descriptionDepartment of Animal Production and Health FMVA UNESP-
Descrição: dc.descriptionCenter for Research and Development in Animal Health – General Bacteriology Laboratory Biological Institute-
Descrição: dc.descriptionIndependent Statistical Analyst-
Descrição: dc.descriptionDepartment of Veterinary Clinical and Surgical Sciences FCAV UNESP-
Descrição: dc.descriptionDepartment of Veterinary Clinical Surgery and Animal Reproduction Animal FMVA-UNESP-
Descrição: dc.descriptionDepartment of Pathology Reproduction and One Health FCAV UNESP-
Descrição: dc.descriptionDepartment of Animal Production and Health FMVA UNESP-
Descrição: dc.descriptionCAPES: 001-
Formato: dc.format37-47-
Idioma: dc.languageen-
Relação: dc.relationVeterinary Ophthalmology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectantimicrobials-
Palavras-chave: dc.subjectcornea-
Palavras-chave: dc.subjectdog-
Palavras-chave: dc.subjectmicroorganisms-
Palavras-chave: dc.subjectpublic health-
Título: dc.titlePrevalence and antibiotic resistance in bacterial isolates of dogs with ulcerative keratitis in São Paulo State, Brazil-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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