A network-based approach to understanding gene–biological processes affecting economically important traits of Nelore cattle

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorEdson Antônio Velano University (UNIFENAS)-
Autor(es): dc.contributorFederal University of Alfenas (UNIFAL)-
Autor(es): dc.contributorNational Center for Research in Energy and Materials (CNPEM)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade Federal de Viçosa (UFV)-
Autor(es): dc.creatorCorrêa, Mariely Simone Lopes-
Autor(es): dc.creatorSilva, Evandro Neves-
Autor(es): dc.creatordos Santos, Thaís Cristina Ferreira-
Autor(es): dc.creatorSimielli Fonseca, Larissa Fernanda-
Autor(es): dc.creatorMagalhães, Ana Fabrícia Braga-
Autor(es): dc.creatorVerardo, Lucas Lima-
Autor(es): dc.creatorde Albuquerque, Lucia Galvão-
Autor(es): dc.creatorSilva, Danielly Beraldo dos Santos-
Data de aceite: dc.date.accessioned2025-08-21T20:25:40Z-
Data de disponibilização: dc.date.available2025-08-21T20:25:40Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-01-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1111/age.13389-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/298091-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/298091-
Descrição: dc.descriptionThis study aimed to build gene–biological process networks with differentially expressed genes associated with economically important traits of Nelore cattle from 17 previous studies. The genes were clustered into three groups by evaluated traits: group 1, production traits; group 2, carcass traits; and group 3, meat quality traits. For each group, a gene–biological process network analysis was performed with the differentially expressed genes in common. For production traits, 37 genes were found in common, of which 13 genes were enriched for six Gene Ontology (GO) terms; these terms were not functionally grouped. However, the enriched GO terms were related to homeostasis, the development of muscles and the immune system. For carcass traits, four genes were found in common. Thus, it was not possible to functionally group these genes into a network. For meat quality traits, the analysis revealed 222 genes in common. CSRP3 was the only gene differentially expressed in all three groups. Non-redundant biological terms for clusters of genes were functionally grouped networks, reflecting the cross-talk between all biological processes and genes involved. Many biological processes and pathways related to muscles, the immune system and lipid metabolism were enriched, such as striated muscle cell development and triglyceride metabolic processes. This study provides insights into the genetic mechanisms of production, carcass and meat quality traits of Nelore cattle. This information is fundamental for a better understanding of the complex traits and could help in planning strategies for the production and selection systems of Nelore cattle.-
Descrição: dc.descriptionEdson Antônio Velano University (UNIFENAS), Minas Gerais-
Descrição: dc.descriptionFederal University of Alfenas (UNIFAL), Minas Gerais-
Descrição: dc.descriptionNational Center for Research in Energy and Materials (CNPEM), São Paulo-
Descrição: dc.descriptionSchool of Agricultural and Veterinarian Sciences São Paulo State University (UNESP), São Paulo-
Descrição: dc.descriptionDepartment of Animal Science Federal University of Vales do Jequitinhonha e Mucuri (UFVJM), Minas Gerais-
Descrição: dc.descriptionSchool of Agricultural and Veterinarian Sciences São Paulo State University (UNESP), São Paulo-
Formato: dc.format55-65-
Idioma: dc.languageen-
Relação: dc.relationAnimal Genetics-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectbiological processes-
Palavras-chave: dc.subjectbovine-
Palavras-chave: dc.subjectcomplex traits-
Palavras-chave: dc.subjectgene-
Palavras-chave: dc.subjectRNA-seq-
Palavras-chave: dc.subjecttranscriptomics-
Título: dc.titleA network-based approach to understanding gene–biological processes affecting economically important traits of Nelore cattle-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.