Biological responses to imazapic and methyl parathion pesticides in bioinspired lipid membranes and Tilapia fish

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorRubira, Rafael J.G.-
Autor(es): dc.creatorBatista, Victor R.G.-
Autor(es): dc.creatorCorreia, Rafael R.-
Autor(es): dc.creatorPazin, Wallance M.-
Autor(es): dc.creatorMaximino, Mateus D.-
Autor(es): dc.creatorRuiz, Gilia C.M.-
Autor(es): dc.creatorTeixeira, Giovana R.-
Autor(es): dc.creatorJob, Aldo E.-
Data de aceite: dc.date.accessioned2025-08-21T18:28:24Z-
Data de disponibilização: dc.date.available2025-08-21T18:28:24Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2023-09-15-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.jhazmat.2023.131943-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/297977-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/297977-
Descrição: dc.descriptionPesticide misuse has well-documented detrimental effects on ecosystems, with Nile tilapia (Oreochromis niloticus) being particularly vulnerable. The current study focuses on the impact of widely used sugarcane crop pesticides, Imazapic (IMZ) and Methyl Parathion (MP), on tilapia gill tissues and their lipid membranes. This investigation was motivated by the specific role of the lipid membrane in transport regulation. Bioinspired cell membrane models, including Langmuir monolayers and liposomes (LUVs and GUVs), were utilized to explore the interaction of IMZ and MP. The results revealed electrostatic interactions between IMZ and MP and the polar head groups of lipids, inducing morphological alterations in the lipid bilayer. Tilapia gill tissue exposed to the pesticides exhibited hypertrophic increases in primary and secondary lamellae, total lamellar fusion, vasodilation, and lifting of the secondary lamellar epithelium. These alterations can lead to compromised oxygen absorption by fish and subsequent mortality. This study not only highlights the harmful effects of the pesticides IMZ and MP, but also emphasizes the crucial role of water quality in ecosystem well-being, even at minimal pesticide concentrations. Understanding these impacts can better inform management practices to safeguard aquatic organisms and preserve ecosystem health in pesticide-affected environments.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionSão Paulo State University (Unesp) School of Technology and Sciences, SP-
Descrição: dc.descriptionSão Paulo State University (Unesp) School of Sciences, SP-
Descrição: dc.descriptionSão Paulo State University (Unesp) School of Technology and Sciences, SP-
Descrição: dc.descriptionSão Paulo State University (Unesp) School of Sciences, SP-
Descrição: dc.descriptionCNPq: 311368/2022-0-
Idioma: dc.languageen-
Relação: dc.relationJournal of Hazardous Materials-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectDOPC-
Palavras-chave: dc.subjectFish gills-
Palavras-chave: dc.subjectGUVs-
Palavras-chave: dc.subjectLangmuir films-
Palavras-chave: dc.subjectLUVs-
Palavras-chave: dc.subjectPesticide-
Título: dc.titleBiological responses to imazapic and methyl parathion pesticides in bioinspired lipid membranes and Tilapia fish-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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