Perspectives on Schwann-like cells derived from bone marrow-mesenchymal stem cells: Advancing peripheral nerve injury therapies

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorFerreira, Lucas Vinícius de Oliveira-
Autor(es): dc.creatorAmorim, Rogério Martins-
Data de aceite: dc.date.accessioned2025-08-21T20:59:00Z-
Data de disponibilização: dc.date.available2025-08-21T20:59:00Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.4252/WJSC.V17.I2.102702-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/297815-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/297815-
Descrição: dc.descriptionPeripheral nerve injuries are clinical conditions that often result in functional deficits, compromising patient quality of life. Given the relevance of these injuries, new treatment strategies are constantly being investigated. Although mesenchymal stem cells already demonstrate therapeutic potential due to their paracrine action, the transdifferentiation of these cells into Schwann-like cells (SLCs) represents a significant advancement in nerve injury therapy. Recent studies indicate that SLCs can mimic the functions of Schwann cells, with promising results in animal models. However, challenges remain, such as the diversity of transdifferentiation protocols and the scalability of these therapies for clinical applications. A recent study by Zou et al provided a comprehensive overview of the role of bone marrow-derived mesenchymal stem cells in the treatment of peripheral nerve injuries. Therefore, we would like to discuss and explore the use of SLCs derived from bone marrow-derived mesenchymal stem cells in more detail as a promising alternative in the field of nerve regeneration.-
Descrição: dc.descriptionDepartment of Veterinary Clinic School of Veterinary Medicine and Animal Science São Paulo State University (UNESP), Botucatu-
Descrição: dc.descriptionDepartment of Veterinary Clinic School of Veterinary Medicine and Animal Science São Paulo State University (UNESP), Botucatu-
Idioma: dc.languageen-
Relação: dc.relationWorld Journal of Stem Cells-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCell therapy-
Palavras-chave: dc.subjectNerve repair-
Palavras-chave: dc.subjectPeripheral nervous system-
Palavras-chave: dc.subjectTransdifferentiation-
Palavras-chave: dc.subjectTransplantation-
Título: dc.titlePerspectives on Schwann-like cells derived from bone marrow-mesenchymal stem cells: Advancing peripheral nerve injury therapies-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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