Comparison of different bone substitutes in the repair of rat calvaria critical size defects: questioning the need for alveolar ridge presentation

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorFaculty of Dentistry of Barretos-
Autor(es): dc.contributorUniversity of Alberta-
Autor(es): dc.contributorSchool of Dentistry Ilapeo-
Autor(es): dc.creatorTheodoro, Letícia Helena-
Autor(es): dc.creatorCampista, Christian Cézane Cardoso-
Autor(es): dc.creatorBury, Luiz Lordêlo-
Autor(es): dc.creatorSouza, Ricardo Guanaes Barbosa de-
Autor(es): dc.creatorMuniz, Yuri Santos-
Autor(es): dc.creatorLongo, Mariéllen-
Autor(es): dc.creatorMulinari-Santos, Gabriel-
Autor(es): dc.creatorErvolino, Edilson-
Autor(es): dc.creatorLevin, Liran-
Autor(es): dc.creatorGarcia, Valdir Gouveia-
Data de aceite: dc.date.accessioned2025-08-21T16:15:57Z-
Data de disponibilização: dc.date.available2025-08-21T16:15:57Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-04-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3290/j.qi.b4955867-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/297804-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/297804-
Descrição: dc.descriptionObjective: This study aimed to evaluate the effectiveness of biomaterials in bone healing of critical bone defects created by piezoelectric surgery in rat calvaria. Method and materials: Histomorphologic analysis was performed to assess bone regeneration and tissue response. Fifty animals were randomized into five groups with one of the following treatments: Control group (n = 10), spontaneous blood clot formation with no bone fill; BO group (Bio-Oss, Geistlich Pharma; n = 10), defects were filled with bovine medullary bone substitute; BF group (Bonefill, Bionnovation; n = 10), defects were filled with bovine cortical bone substitute; hydroxyapatite group (n = 10), defects were filled with hydroxyapatite; calcium sulfate group (n = 10), defects were filled with calcium sulfate. Five animals from each group were euthanized at 30 and 45 days. The histomorphometry calculated the percentage of the new bone formation in the bone defect. Results: All data obtained were evaluated statistically considering P < .05 as statistically significant. The results demonstrated the potential of all biomaterials for enhancing bone regeneration. The findings showed no statistical differences between all the biomaterials at 30 and 45 days including the control group without bone grafting. Conclusion: In conclusion, the tested biomaterials presented an estimated capacity of osteoconduction, statistically nonsignificant between them. In addition, the selection of biomaterial should consider the specific clinical aspect, resorption rates, size of the particle, and desired bone healing responses. It is important to emphasize that in some cases, using no bone filler might provide comparable results with reduced cost and possible complications questioning the very frequent use of ridge presentation procedures.-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery School of Dentistry São Paulo State University (UNESP), Araçatuba-
Descrição: dc.descriptionGraduate Program in Dentistry Faculty of Dentistry of Barretos, Barretos-
Descrição: dc.descriptionPeriodontology Faculty of Medicine and Dentistry University of Alberta-
Descrição: dc.descriptionLatin American Institute of Dental Research and Teaching School of Dentistry Ilapeo, Paraná, PR-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery School of Dentistry São Paulo State University (UNESP), Araçatuba-
Formato: dc.format328-334-
Idioma: dc.languageen-
Relação: dc.relationQuintessence International-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectbone-
Palavras-chave: dc.subjectbone substitutes-
Palavras-chave: dc.subjectextraction-
Palavras-chave: dc.subjectimplants-
Palavras-chave: dc.subjectwound healing-
Título: dc.titleComparison of different bone substitutes in the repair of rat calvaria critical size defects: questioning the need for alveolar ridge presentation-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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