Engineered organoids for biomedical applications

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorTerasaki Institute for Biomedical Innovation (TIBI)-
Autor(es): dc.contributorCalifornia Institute of Technology-
Autor(es): dc.contributorGhent University Hospital-
Autor(es): dc.contributorKTH Royal Institute of Technology-
Autor(es): dc.contributorUniversidade Estadual de Campinas (UNICAMP)-
Autor(es): dc.contributorAmirkabir University of Technology (Tehran Polytechnic)-
Autor(es): dc.contributorCalifornia State University-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversity of Veterinary Medicine and Pharmacy in Kosice-
Autor(es): dc.contributorUniversity of Victoria-
Autor(es): dc.contributorViral Biotechnology Laboratory-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorPohang University of Science and Technology (POSTECH)-
Autor(es): dc.contributorKorea University-
Autor(es): dc.creatorRoberto de Barros, Natan-
Autor(es): dc.creatorWang, Canran-
Autor(es): dc.creatorMaity, Surjendu-
Autor(es): dc.creatorPeirsman, Arne-
Autor(es): dc.creatorNasiri, Rohollah-
Autor(es): dc.creatorHerland, Anna-
Autor(es): dc.creatorErmis, Menekse-
Autor(es): dc.creatorKawakita, Satoru-
Autor(es): dc.creatorGregatti Carvalho, Bruna-
Autor(es): dc.creatorHosseinzadeh Kouchehbaghi, Negar-
Autor(es): dc.creatorDonizetti Herculano, Rondinelli-
Autor(es): dc.creatorTirpáková, Zuzana-
Autor(es): dc.creatorMohammad Hossein Dabiri, Seyed-
Autor(es): dc.creatorLucas Tanaka, Jean-
Autor(es): dc.creatorFalcone, Natashya-
Autor(es): dc.creatorChoroomi, Auveen-
Autor(es): dc.creatorChen, RunRun-
Autor(es): dc.creatorHuang, Shuyi-
Autor(es): dc.creatorZisblatt, Elisheva-
Autor(es): dc.creatorHuang, Yixuan-
Autor(es): dc.creatorRashad, Ahmad-
Autor(es): dc.creatorKhorsandi, Danial-
Autor(es): dc.creatorGangrade, Ankit-
Autor(es): dc.creatorVoskanian, Leon-
Autor(es): dc.creatorZhu, Yangzhi-
Autor(es): dc.creatorLi, Bingbing-
Autor(es): dc.creatorAkbari, Mohsen-
Autor(es): dc.creatorLee, Junmin-
Autor(es): dc.creatorRemzi Dokmeci, Mehmet-
Autor(es): dc.creatorKim, Han-Jun-
Autor(es): dc.creatorKhademhosseini, Ali-
Data de aceite: dc.date.accessioned2025-08-21T19:59:08Z-
Data de disponibilização: dc.date.available2025-08-21T19:59:08Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2023-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.addr.2023.115142-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/297785-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/297785-
Descrição: dc.descriptionAs miniaturized and simplified stem cell-derived 3D organ-like structures, organoids are rapidly emerging as powerful tools for biomedical applications. With their potential for personalized therapeutic interventions and high-throughput drug screening, organoids have gained significant attention recently. In this review, we discuss the latest developments in engineering organoids and using materials engineering, biochemical modifications, and advanced manufacturing technologies to improve organoid culture and replicate vital anatomical structures and functions of human tissues. We then explore the diverse biomedical applications of organoids, including drug development and disease modeling, and highlight the tools and analytical techniques used to investigate organoids and their microenvironments. We also examine the latest clinical trials and patents related to organoids that show promise for future clinical translation. Finally, we discuss the challenges and future perspectives of using organoids to advance biomedical research and potentially transform personalized medicine.-
Descrição: dc.descriptionTerasaki Institute for Biomedical Innovation (TIBI)-
Descrição: dc.descriptionAndrew and Peggy Cherng Department of Medical Engineering Division of Engineering and Applied Science California Institute of Technology-
Descrição: dc.descriptionPlastic and Reconstructive Surgery Ghent University Hospital-
Descrição: dc.descriptionDivision of Nanobiotechnology Department of Protein Science Science for Life Laboratory KTH Royal Institute of Technology-
Descrição: dc.descriptionDepartment of Material and Bioprocess Engineering School of Chemical Engineering University of Campinas (UNICAMP)-
Descrição: dc.descriptionDepartment of Textile Engineering Amirkabir University of Technology (Tehran Polytechnic), Hafez Avenue-
Descrição: dc.descriptionAutonomy Research Center for STEAHM (ARCS) California State University-
Descrição: dc.descriptionSão Paulo State University (UNESP) Bioengineering and Biomaterials Group School of Pharmaceutical Sciences, SP-
Descrição: dc.descriptionDepartment of Biology and Physiology University of Veterinary Medicine and Pharmacy in Kosice, Komenskeho 73-
Descrição: dc.descriptionLaboratory for Innovations in Micro Engineering (LiME) Department of Mechanical Engineering University of Victoria-
Descrição: dc.descriptionButantan Institute Viral Biotechnology Laboratory, SP-
Descrição: dc.descriptionUniversity of São Paulo (USP), SP-
Descrição: dc.descriptionDepartment of Materials Science and Engineering Pohang University of Science and Technology (POSTECH), Gyeongbuk-
Descrição: dc.descriptionCollege of Pharmacy Korea University-
Descrição: dc.descriptionSão Paulo State University (UNESP) Bioengineering and Biomaterials Group School of Pharmaceutical Sciences, SP-
Idioma: dc.languageen-
Relação: dc.relationAdvanced Drug Delivery Reviews-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectDisease modeling-
Palavras-chave: dc.subjectOrganoids-
Palavras-chave: dc.subjectRegenerative medicine-
Palavras-chave: dc.subjectSpheroids-
Palavras-chave: dc.subjectStem cell-
Palavras-chave: dc.subjectTherapies-
Título: dc.titleEngineered organoids for biomedical applications-
Tipo de arquivo: dc.typevídeo-
Aparece nas coleções:Repositório Institucional - Unesp

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