The use of mouthwash containing trimetaphosphate as an adjunct therapy to fluoridated toothpaste reduces enamel demineralization

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorGruba, Amanda Scarpin-
Autor(es): dc.creatorNunes, Gabriel Pereira-
Autor(es): dc.creatorDanelon, Marcelle-
Autor(es): dc.creatorGonçalves, Francyenne Maira Castro-
Autor(es): dc.creatorde Toledo, Priscila Toninatto Alves-
Autor(es): dc.creatorFerreira, Mayra Fernanda-
Autor(es): dc.creatorPoli, Maria Clara Faria-
Autor(es): dc.creatorDelbem, Alberto Carlos Botazzo-
Data de aceite: dc.date.accessioned2025-08-21T22:52:11Z-
Data de disponibilização: dc.date.available2025-08-21T22:52:11Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-06-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.jdent.2024.104966-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/297748-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/297748-
Descrição: dc.descriptionIntroduction: The decline in dental caries has been attributed to the widespread use of fluoride (F). Two forms of presentation are fluoridated toothpaste (FT) and mouthwash (MW), widely used by the population. Materials and methods: This study aimed to evaluate in vitro the effects of combining FT and MW, whether supplemented with sodium trimetaphosphate (TMP) or not, on dental enamel demineralization. Bovine enamel blocks (n = 60) were selected based on initial surface hardness (SHi) and divided into 5 experimental groups (n = 12 each): I) Placebo Toothpaste (without F/TMP); II) 1100 ppm F Toothpaste (FT); III) 1100F associated with a MW at 100 ppm F (FT + MW 100F); IV) 1100F associated with a MW at 225 ppm F (FT + MW 250F); and V) 1100F associated with a MW at 100 ppm F supplemented with 0.4 % TMP (FT + MW 100F-TMP). The blocks were treated twice a day, undergoing 5 pH cycles over 7 days. Thus, the percentage change in surface hardness (%SH), integrated subsurface hardness loss (ΔKHN), and the concentration of F, phosphorus (P), and calcium (Ca) in the enamel were determined. The data were submitted to ANOVA and Student-Newman-Keuls test (p < 0.001). Results: The 1100F group was statistically inferior to the groups associated with MW for %SH, ΔKHN, and the concentration of P and Ca in the enamel (p < 0.001). Blocks treated with FT + MW 225F and FT + MW 100F-TMP showed significantly lower %SH compared to the other groups (p < 0.001). The FT + MW 100F - TMP group exhibited the lowest depth mineral loss (ΔKHN), and higher concentration de P in enamel (p < 0.001). Conclusion: The adjunct use of MW with FT produces a greater protective effect in inhibiting enamel demineralization, and the supplementation of TMP to the MW with 100F provides a superior effect compared to MW with 225F. Clinical significance: This combination of treatments could be regarded as one of several alternative fluoride supplements for subjects at elevated risk of caries.-
Descrição: dc.descriptionDepartment of Preventive and Restorative Dentistry Araçatuba School of Dentistry São Paulo State University - UNESP, SP-
Descrição: dc.descriptionDepartment of Preventive and Restorative Dentistry Araçatuba School of Dentistry São Paulo State University - UNESP, SP-
Idioma: dc.languageen-
Relação: dc.relationJournal of Dentistry-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectDental enamel-
Palavras-chave: dc.subjectFluorine-
Palavras-chave: dc.subjectMouthwashes-
Palavras-chave: dc.subjectPhosphates-
Palavras-chave: dc.subjectTooth demineralization-
Palavras-chave: dc.subjectToothpastes-
Título: dc.titleThe use of mouthwash containing trimetaphosphate as an adjunct therapy to fluoridated toothpaste reduces enamel demineralization-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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