Influence of bioceramic sealers on dentinal tubule penetration and antimicrobial effectiveness: a systematic review and meta-analysis of in vitro studies

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorSeron, Marcelo Augusto-
Autor(es): dc.creatorNunes, Gabriel Pereira-
Autor(es): dc.creatorFerrisse, Tulio Morandin-
Autor(es): dc.creatorStrazzi-Sahyon, Henrico Badaoui-
Autor(es): dc.creatordos Santos, Paulo Henrique-
Autor(es): dc.creatorGomes-Filho, João Eduardo-
Autor(es): dc.creatorCintra, Luciano Tavares Angelo-
Autor(es): dc.creatorSivieri-Araujo, Gustavo-
Data de aceite: dc.date.accessioned2025-08-21T21:15:17Z-
Data de disponibilização: dc.date.available2025-08-21T21:15:17Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-07-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s10266-024-00904-6-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/297723-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/297723-
Descrição: dc.descriptionThe aim of this systematic review and meta-analysis (SRM) was to evaluate whether bioceramic sealers have better penetration capacity in dentinal tubules and antimicrobial activity when compared to AH Plus® sealer. This SRM was recorded in the Open Science Framework database and followed the guidelines of the PRISMA 2020. Five databases were searched by two independent reviewers. Only in vitro studies that evaluated the effects of bioceramic sealers on dentinal tubule penetration and antimicrobial activity outcomes compared to AH Plus® sealer were included. Meta-analysis was conducted using R software, using the effect measure of the standardized mean difference (SMD) and inverse variance method. A modified Joanna Briggs Institute’s Checklist was used for the risk of bias assessment. A total of 1486 studies were identified, and only 54 studies that fulfilled our eligibility criteria were included in this review. There was no statistical difference between the sealers evaluated for dentinal tubule penetration, in the thirds evaluated: coronal SMD 0.58 [0.14; 1.31], p = 0.12; middle SMD 0.07 [0.54; 0.39], p = 0.75; and apical SMD 0.08 [0.73; 0.56], p = 0.80. Both sealers demonstrated similar antimicrobial action (SMD [3.42; 5.32], p = 0.67 and SMD 0.67 [1.89; 0.55], p = 0.28). The studies presented a low risk of bias. Based on the in vitro studies included and according to the limitations of the present review, the data suggest that bioceramic and AH Plus® sealers present similar penetration capacity in dentinal tubules and antimicrobial effect, making them suitable materials to be considered in clinical practice.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionDepartment of Preventive and Restorative Dentistry Araçatuba School of Dentistry São Paulo State University - UNESP, Rua José Bonifácio 1193, SP-
Descrição: dc.descriptionOral Medicine Department of Diagnosis and Surgery Araraquara School of Dentistry São Paulo State University - UNESP, SP-
Descrição: dc.descriptionDepartment of Dental Materials and Prosthodontics Araçatuba School of Dentistry São Paulo State University - UNESP, SP-
Descrição: dc.descriptionDepartment of Preventive and Restorative Dentistry Araçatuba School of Dentistry São Paulo State University - UNESP, Rua José Bonifácio 1193, SP-
Descrição: dc.descriptionOral Medicine Department of Diagnosis and Surgery Araraquara School of Dentistry São Paulo State University - UNESP, SP-
Descrição: dc.descriptionDepartment of Dental Materials and Prosthodontics Araçatuba School of Dentistry São Paulo State University - UNESP, SP-
Descrição: dc.descriptionCAPES: Finance Code 001-
Formato: dc.format672-699-
Idioma: dc.languageen-
Relação: dc.relationOdontology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAntimicrobial activity-
Palavras-chave: dc.subjectCalcium silicate-
Palavras-chave: dc.subjectMeta-analysis-
Palavras-chave: dc.subjectRoot canal sealer-
Palavras-chave: dc.subjectSealer penetration-
Título: dc.titleInfluence of bioceramic sealers on dentinal tubule penetration and antimicrobial effectiveness: a systematic review and meta-analysis of in vitro studies-
Tipo de arquivo: dc.typevídeo-
Aparece nas coleções:Repositório Institucional - Unesp

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