Effectiveness of Bioactive Toothpastes against Dentin Hypersensitivity Using Evaporative and Tactile Analyses: A Randomized Clinical Trial

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniv Anhanguera Sao Paulo-
Autor(es): dc.contributorUniv Metropolitana de Santos UNIMES-
Autor(es): dc.contributorUniv Anhanguera Uniderp-
Autor(es): dc.contributorTrials Res & Dev Inc-
Autor(es): dc.contributorTriplet Biotechnol Solut Inc-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorAlonso, Roberta Caroline Bruschi-
Autor(es): dc.creatorOliveira, Leticia de-
Autor(es): dc.creatorSilva, Jaqueline Alves Batista-
Autor(es): dc.creatorSantos, Williane Bernadete Bezerra dos-
Autor(es): dc.creatorFerreira, Luria Ribeiro de Souza Laranja-
Autor(es): dc.creatorGuiraldo, Ricardo Danil-
Autor(es): dc.creatorVilhena, Fabiano Vieira-
Autor(es): dc.creatorD'Alpino, Paulo Henrique Perlatti-
Data de aceite: dc.date.accessioned2025-08-21T20:42:44Z-
Data de disponibilização: dc.date.available2025-08-21T20:42:44Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-03-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3390/oral4010004-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/297649-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/297649-
Descrição: dc.descriptionThe objective of this study was to investigate and compare the effectiveness of toothpastes containing bioactives to relieve dentin hypersensitivity with that of a commercial desensitizing toothpaste containing REFIX technology, associated or not with a calcium booster. In this double-blind, randomized, parallel-group, multi-center clinical trial, thirty-two volunteers diagnosed with dentin hypersensitivity and qualified to participate were randomized into four groups: (1) Colgate Sensitive Pro-Relief; (2) Sensodyne Repair & Relief; (3) Regenerador Sensitive; and (4) Regenerador Sensitive, associated with a calcium booster. Evaporative and tactile tests were used to check for dentin hypersensitivity in the test subjects. The participants brushed their teeth with one of the toothpastes, and dentin hypersensitivity was immediately tested using a visual analogue scale (VAS), in which the pain was rated on a scale of 0 to 10. Dentin hypersensitivity was measured after one week and after one month of the subjects continuing to use the toothpaste three times per day. Data were statistically analyzed with a non-parametric Friedman test for dependent data (alpha = 0.05). All toothpastes reduced dentin hypersensitivity. In the evaporative test, Sensodyne Protect & Repair and Regenerador Sensitive, associated with the calcium booster, exhibited faster and more effective results in reducing pain caused by dentin hypersensitivity, even after the first use. Colgate Sensitive Pro-Relief was effective only after one week of use. All toothpastes performed well in the tactile test for treating dentin hypersensitivity, and their performance improved over time. Sensodyne Repair & Protect presented the highest overall pain remission after one month (84.6%). The bioactive toothpastes reduced, to a different extent, the tooth hypersensitivity reported by the volunteers. Sensodyne Repair & Relief and Regenerador Sensitive, associated or not with a calcium booster, presented faster and more effective results in reducing pain caused by dentin hypersensitivity.-
Descrição: dc.descriptionUniv Anhanguera Sao Paulo, Sch Dent, BR-06020015 Sao Paulo, SP, Brazil-
Descrição: dc.descriptionUniv Metropolitana de Santos UNIMES, Sch Dent, BR-11045002 Santos, SP, Brazil-
Descrição: dc.descriptionUniv Anhanguera Uniderp, Dept Restorat Dent, BR-79035470 Campo Grande, MS, Brazil-
Descrição: dc.descriptionTrials Res & Dev Inc, BR-17018776 Bauru, SP, Brazil-
Descrição: dc.descriptionTriplet Biotechnol Solut Inc, BR-17015130 Bauru, SP, Brazil-
Descrição: dc.descriptionSao Paulo State Univ UNESP, Sch Sci, BR-17033360 Bauru, SP, Brazil-
Descrição: dc.descriptionSao Paulo State Univ UNESP, Sch Sci, BR-17033360 Bauru, SP, Brazil-
Formato: dc.format36-49-
Idioma: dc.languageen-
Publicador: dc.publisherMdpi-
Relação: dc.relationOral-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectclinical trial-
Palavras-chave: dc.subjectdentin hypersensitivity-
Palavras-chave: dc.subjectdesensitizing-
Palavras-chave: dc.subjecttoothpaste-
Título: dc.titleEffectiveness of Bioactive Toothpastes against Dentin Hypersensitivity Using Evaporative and Tactile Analyses: A Randomized Clinical Trial-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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