Statherin-Derived Peptide Protects against Intrinsic Erosive Enamel Wear in situ

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorTaira, Even Akemi-
Autor(es): dc.creatorFerrari, Carolina Ruis-
Autor(es): dc.creatorCarvalho, Gabriel-
Autor(es): dc.creatorPelá, Vinicius Taioqui-
Autor(es): dc.creatorVentura, Talita Mendes Oliveira-
Autor(es): dc.creatorCrusca, Edson-
Autor(es): dc.creatorMarchetto, Reinaldo-
Autor(es): dc.creatorBuzalaf, Marília Afonso Rabelo-
Data de aceite: dc.date.accessioned2025-08-21T15:56:36Z-
Data de disponibilização: dc.date.available2025-08-21T15:56:36Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2023-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1159/000541403-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/297624-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/297624-
Descrição: dc.descriptionIntroduction: This in situ study investigated the protective effect of a solution containing statherin-derived peptide (StatpSpS) against enamel intrinsic erosion (ERO). Methods: Fifteen volunteers wore appliances containing 2 bovine specimens. The samples were subjected to ERO with HCl, mimicking dental ERO by intrinsic acid. The volunteers participated in 3 phases (double-blind and crossover): (1) deionized water (negative control); (2) commercial solution containing SnCl2/NaF/AmF (800 ppm Sn+2, 500 ppm F-, pH 4.5) (positive control); (3) solution containing 1.88 × 10-5 M StatpSpS. Four times a day, the volunteers administered one drop of the solutions (50 μL, 1 min) on each specimen. After the treatment, erosive challenges were performed extraorally with 0.01 M HCl (pH 2.0, 4 times/day, 1 min, 150 mL). Enamel wear was assessed by profilometry. Data were analyzed by one-way RM-ANOVA/Bonferroni s tests (p < 0.05). Results: In terms of the treatments, both the commercial solution (SnCl2/NaF/AmF) and StatpSpS significantly reduced the wear when compared to the negative control (p < 0.01), without significant differences between them (p > 0.05). Conclusion: The solution containing StatpSpS demonstrated protection against enamel intrinsic erosive wear. This study marks a significant advancement in the prevention of intrinsic erosive wear, utilizing StatpSpS in acquired pellicle engineering procedures.-
Descrição: dc.descriptionDepartment of Biological Sciences Bauru School of Dentistry University of São Paulo-
Descrição: dc.descriptionChemistry Institute Paulista State University-
Descrição: dc.descriptionChemistry Institute Paulista State University-
Idioma: dc.languageen-
Relação: dc.relationCaries Research-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAcquired pellicle-
Palavras-chave: dc.subjectErosive tooth wear-
Palavras-chave: dc.subjectPrevention-
Palavras-chave: dc.subjectStatherin-
Título: dc.titleStatherin-Derived Peptide Protects against Intrinsic Erosive Enamel Wear in situ-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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