Global neonatal perioperative mortality: A systematic review and meta-analysis

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorBraz, Leandro G.-
Autor(es): dc.creatorBraz, Jose Reinaldo C.-
Autor(es): dc.creatorTiradentes, Teofilo Augusto A.-
Autor(es): dc.creatorSoares, Joao Vitor A.-
Autor(es): dc.creatorCorrente, Jose E.-
Autor(es): dc.creatorModolo, Norma Sueli P.-
Autor(es): dc.creatordo Nascimento Junior, Paulo-
Autor(es): dc.creatorBraz, Mariana G.-
Data de aceite: dc.date.accessioned2025-08-21T18:58:22Z-
Data de disponibilização: dc.date.available2025-08-21T18:58:22Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-06-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.jclinane.2024.111407-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/297558-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/297558-
Descrição: dc.descriptionStudy objective: There are large differences in health care among countries. A higher perioperative mortality rate (POMR) in neonates than in older children and adults has been recognized worldwide. The aim of this study was to provide a systematic review of published 24-h and 30-day POMRs in neonates from 2011 to 2022 in countries with different Human Development Index (HDI) levels. Design and setting: A systematic review with a meta-analysis of studies that reported 24-h and 30-day POMRs in neonates was performed. We searched the databases from January 2011 to July 30, 2022. Measurements: The POMRs (per 10,000 procedures under anesthesia) were analyzed according to country HDI. The HDI levels ranged from 0 to 1, representing the lowest and highest levels, respectively (very-high-HDI: ≥ 0.800, high-HDI: 0.700–0.799, medium-HDI: 0.550–0.699, and low-HDI: < 0.550). The magnitude of the POMRs by country HDI was studied using meta-analysis. Main results: Eighteen studies from 45 countries were included. The 24-h (n = 96 deaths) and 30-day (n = 459 deaths) POMRs were analyzed from 33,729 anesthetic procedures. The odds ratios (ORs) of the 24-h POMR in low-HDI countries were higher than those in very-high- (OR 8.4, 95% CI 1.7–40.4; p = 0.008), high- (OR 7.3, 95% CI 2.2–24.4; p = 0.001) and medium-HDI countries (OR 7.7, 95% CI 3.1–18.7; p < 0.0001) but with no odds differences between very-high- and high-HDI countries (p = 0.879), very-high- and medium-HDI countries (p = 0.915) and high- and medium-HDI countries (p = 0.689). The odds of a 30-day POMR in low-HDI countries were higher than those in very-high-HDI countries (OR 6.9, 95% CI 1.9–24.6; p = 0.002) but not in high-HDI countries (OR 1.4, 95% CI 0.6–3.0; p = 0.396). Conclusions: The review demonstrated very high global POMRs in a surgical population of neonates independent of the country HDI level. We identified differences in 24-h and 30-day POMRs between low-HDI countries and other countries with higher HDI levels.-
Descrição: dc.descriptionAnesthesia Cardiac Arrest and Mortality Study Commission Department of Surgical Specialties and Anesthesiology Botucatu Medical School Sao Paulo State University - UNESP, SP-
Descrição: dc.descriptionDepartment of Biostatistics Institute of Biosciences Sao Paulo State University - UNESP, SP-
Descrição: dc.descriptionAnesthesia Cardiac Arrest and Mortality Study Commission Department of Surgical Specialties and Anesthesiology Botucatu Medical School Sao Paulo State University - UNESP, SP-
Descrição: dc.descriptionDepartment of Biostatistics Institute of Biosciences Sao Paulo State University - UNESP, SP-
Idioma: dc.languageen-
Relação: dc.relationJournal of Clinical Anesthesia-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAnesthesia-
Palavras-chave: dc.subjectHigh-income population-
Palavras-chave: dc.subjectLow-income population-
Palavras-chave: dc.subjectMortality-
Palavras-chave: dc.subjectNewborn-
Palavras-chave: dc.subjectSurgery-
Título: dc.titleGlobal neonatal perioperative mortality: A systematic review and meta-analysis-
Tipo de arquivo: dc.typevídeo-
Aparece nas coleções:Repositório Institucional - Unesp

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