Size-controlled hydroxyapatite particle nucleation in natural rubber latex membranes

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversity of Aveiro-
Autor(es): dc.contributorTerasaki Institute for Biomedical Innovation (TIBI)-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.creatorPiazza, Rodolfo Debone-
Autor(es): dc.creatorPinto, Gabriel Cardoso-
Autor(es): dc.creatorVisoná, Vitor Mattos-
Autor(es): dc.creatorHerculano, Rondinelli Donizetti-
Autor(es): dc.creatordos Santos, Lindomar Soares-
Autor(es): dc.creatorPrimo, Fernando Lucas-
Autor(es): dc.creatorFernandes, Mariza Aires-
Autor(es): dc.creatorde Souza, Francisley A.-
Autor(es): dc.creatorMarques, Rodrigo Fernando Costa-
Autor(es): dc.creatorGuastaldi, Antônio Carlos-
Data de aceite: dc.date.accessioned2025-08-21T17:45:57Z-
Data de disponibilização: dc.date.available2025-08-21T17:45:57Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2025-06-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.matchemphys.2025.130606-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/297303-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/297303-
Descrição: dc.descriptionBone regeneration effectively treats fractures, but factors such as injury severity and age can delay healing. In these cases, implants or bone transplants may be required for repair. This study employed the biomimetic approach to fabricate composite membranes for bone tissue engineering. The inherent stretchability, barrier properties, and angiogenic potential of natural rubber latex were integrated with the excellent osteoconductive and osseointegrative properties of hydroxyapatite (HA). By controlling the biomimetic incubation, size-controlled CaP nucleation and growth within the latex matrix were achieved, ranging from nano to micro-scale. Characterization confirmed the successful formation of CaP-latex composites with enhanced surface roughness and wettability. Finally, the cytotoxicity analysis in fibroblasts showed that the Latex_CaP membranes were non-toxic. This combination of material properties offers significant potential for the development of advanced bone grafts with improved bioactivity and enhanced tissue regeneration.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionFinanciadora de Estudos e Projetos-
Descrição: dc.descriptionLaboratory of Magnetic Materials and Colloids Department of Analytical Physico-chemistry and Inorganic Chemistry Institute of Chemistry São Paulo State University (UNESP), SP-
Descrição: dc.descriptionAveiro Institute of Materials - CICECO University of Aveiro-
Descrição: dc.descriptionBioengineering & Biomaterials Group School of Pharmaceutical Sciences São Paulo State University (UNESP), SP-
Descrição: dc.descriptionTerasaki Institute for Biomedical Innovation (TIBI), 11507 W Olympic Blvd-
Descrição: dc.descriptionFaculty of Philosophy Sciences and Languages of Ribeirão Preto University of São Paulo (USP), 3900 Bandeirantes Avenue, Ribeirão Preto, SP-
Descrição: dc.descriptionDepartment of Bioprocess and Biotechnology Engineering School of Pharmaceutical Sciences São Paulo State University—UNESP, São Paulo-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery School of Dentistry São Paulo State University (UNESP), SP-
Descrição: dc.descriptionGroup of Biomaterials Department of Analytical Physico-chemistry and Inorganic Chemistry Institute of Chemistry São Paulo State University (UNESP), SP-
Descrição: dc.descriptionLaboratory of Magnetic Materials and Colloids Department of Analytical Physico-chemistry and Inorganic Chemistry Institute of Chemistry São Paulo State University (UNESP), SP-
Descrição: dc.descriptionBioengineering & Biomaterials Group School of Pharmaceutical Sciences São Paulo State University (UNESP), SP-
Descrição: dc.descriptionDepartment of Bioprocess and Biotechnology Engineering School of Pharmaceutical Sciences São Paulo State University—UNESP, São Paulo-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery School of Dentistry São Paulo State University (UNESP), SP-
Descrição: dc.descriptionGroup of Biomaterials Department of Analytical Physico-chemistry and Inorganic Chemistry Institute of Chemistry São Paulo State University (UNESP), SP-
Idioma: dc.languageen-
Relação: dc.relationMaterials Chemistry and Physics-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBiomimetic method-
Palavras-chave: dc.subjectCalcium phosphate-
Palavras-chave: dc.subjectNatural rubber latex-
Palavras-chave: dc.subjectTissue engineering-
Título: dc.titleSize-controlled hydroxyapatite particle nucleation in natural rubber latex membranes-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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