DRESS syndrome: an interaction between drugs, latent viruses, and the immune system

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorCentro Universitário Faculdade de Medicina do ABC-
Autor(es): dc.contributor(Fundação Lusíada)-
Autor(es): dc.contributorHospital de Doenças Tropicais de Goiás-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUCARE Center and ADCARE-
Autor(es): dc.contributorUniversidade do Estado do Amazonas-
Autor(es): dc.creatorCriado, Paulo Ricardo-
Autor(es): dc.creatorIanhez, Mayra-
Autor(es): dc.creatorMiot, Hélio Amante-
Autor(es): dc.creatorCriado, Roberta Fachini Jardim-
Autor(es): dc.creatorTalhari, Carolina-
Autor(es): dc.creatorMüller Ramos, Paulo-
Data de aceite: dc.date.accessioned2025-08-21T19:42:26Z-
Data de disponibilização: dc.date.available2025-08-21T19:42:26Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.abd.2023.12.010-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/297212-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/297212-
Descrição: dc.descriptionDrug-induced hypersensitivity syndrome, also known as DRESS syndrome, is a serious and potentially fatal reaction that occurs in response to prolonged use (generally between 14 and 60 days) of certain drugs, and which has no predilection for gender or age group. It is believed that DRESS syndrome has a genetic basis and results from the interaction between metabolites of certain pharmacological groups, reactivation of latent viruses (especially from the Herpesviridae family), and a cellular immune response. The classic manifestation of DRESS syndrome includes a generalized rash accompanied by fever, eosinophilia, lymphadenopathy, and systemic involvement such as hepatitis, nephritis, or pneumonitis. With the continuous increase in the availability of drugs and the aging of the population, there is a favorable scenario for the development of adverse drug reactions. Physicians should be prepared for the early diagnosis of DRESS syndrome, the identification and immediate suspension of the drug involved, and also manage systemic involvement, which may require prolonged immunosuppressive therapy. This article provides an update on the clinical, physiopathological and therapeutic aspects of DRESS syndrome.-
Descrição: dc.descriptionCentro Universitário Faculdade de Medicina do ABC, SP-
Descrição: dc.descriptionFaculdade de Ciências Médicas de Santos (Fundação Lusíada), SP-
Descrição: dc.descriptionDepartment of Dermatology Hospital de Doenças Tropicais de Goiás, GO-
Descrição: dc.descriptionDepartment of Infectology Dermatology Imaging Diagnosis and Radiotherapy Faculty of Medicine Universidade Estadual Paulista, SP-
Descrição: dc.descriptionAlergoskin Alergia e Dermatologia UCARE Center and ADCARE, SP-
Descrição: dc.descriptionDepartment of Dermatology Universidade do Estado do Amazonas, AM-
Descrição: dc.descriptionDepartment of Infectology Dermatology Imaging Diagnosis and Radiotherapy Faculty of Medicine Universidade Estadual Paulista, SP-
Formato: dc.format104-120-
Idioma: dc.languageen-
Relação: dc.relationAnais Brasileiros de Dermatologia-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectDrug eruption-
Palavras-chave: dc.subjectDrug hypersensitivity syndrome-
Palavras-chave: dc.subjectDrug-related side effects and adverse reactions-
Palavras-chave: dc.subjectEosinophilia-
Palavras-chave: dc.subjectSubstance and drug-induced liver disease-
Título: dc.titleDRESS syndrome: an interaction between drugs, latent viruses, and the immune system-
Tipo de arquivo: dc.typevídeo-
Aparece nas coleções:Repositório Institucional - Unesp

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