Obtaining of Antibacterial Nanoporous Layer on Ti7.5Mo Alloy Surface Combining Alkaline Treatment and Silver: In Vitro Studies

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorInstitute of Physics and Chemistry-
Autor(es): dc.creatorMathias de Souza, Barbara Lois-
Autor(es): dc.creatorEscada, Ana Lúcia do Amaral-
Autor(es): dc.creatorCosta Fernandes, Célio Junior da-
Autor(es): dc.creatorde Almeida, Gerson Santos-
Autor(es): dc.creatorZambuzzi, Willian Fernando-
Autor(es): dc.creatorCapellato, Patricia-
Autor(es): dc.creatorSachs, Daniela-
Autor(es): dc.creatorRosifini Alves, Ana Paula-
Data de aceite: dc.date.accessioned2025-08-21T21:21:27Z-
Data de disponibilização: dc.date.available2025-08-21T21:21:27Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2023-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3390/coatings14010052-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/297207-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/297207-
Descrição: dc.descriptionIn the present study, a combination of alkaline treatment and silver was used to produce an antibacterial nanolayer on the Ti7.5Mo alloy surface. The antibacterial response and osteogenesis were evaluated by assessing the adhesion and proliferation of S. aureus and S. epidermidis, as well as the adhesion, viability, and expression levels of genes involved in osteogenic differentiation in the mouse pre-osteoblast cell line MC3T3-E1. The potential stimulus of extracellular remodeling was evaluated using zymography. Our results showed that there is no difference in cytotoxicity after silver immobilization. Protein activity (MMP9) progressively increased for theTi7.5Mo alloy, both untreated and after alkaline treatment. However, the highest increase in protein activity was observed when the alloy was in direct contact with immobilized silver nanoparticles. The surfaces containing silver showed a better response in terms of colony formation, meaning that less bacterial adhesion was detected. The results showed that the layer formed was effective in reducing bacterial activity without altering cell viability.-
Descrição: dc.descriptionUnesp São Paulo State Univesity School of Engineering and Sciences, Campus, Guaratinguetá, SP-
Descrição: dc.descriptionUnesp São Paulo State University School of Engineering, Ilha Solteira Campus, SP-
Descrição: dc.descriptionUnesp São Paulo State University Institute of Biosciences, Distrito de Rubião Júnior, s/n, SP-
Descrição: dc.descriptionUnifei—Federal University of Itajubá Institute of Physics and Chemistry, MG-
Descrição: dc.descriptionUnesp São Paulo State Univesity School of Engineering and Sciences, Campus, Guaratinguetá, SP-
Descrição: dc.descriptionUnesp São Paulo State University School of Engineering, Ilha Solteira Campus, SP-
Descrição: dc.descriptionUnesp São Paulo State University Institute of Biosciences, Distrito de Rubião Júnior, s/n, SP-
Idioma: dc.languageen-
Relação: dc.relationCoatings-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectbiocompatibility-
Palavras-chave: dc.subjectchemical method-
Palavras-chave: dc.subjectnanoporous layer-
Palavras-chave: dc.subjectsilver-
Título: dc.titleObtaining of Antibacterial Nanoporous Layer on Ti7.5Mo Alloy Surface Combining Alkaline Treatment and Silver: In Vitro Studies-
Tipo de arquivo: dc.typelivro digital-
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