Clinical and hematological alterations in dogs during experimental envenomation with Crotalus durissus terrificus venom and treated with antiophidic serum

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorNogueira, R. M. B.-
Autor(es): dc.creatorSakate, M.-
Data de aceite: dc.date.accessioned2021-03-10T18:00:10Z-
Data de disponibilização: dc.date.available2021-03-10T18:00:10Z-
Data de envio: dc.date.issued2014-05-20-
Data de envio: dc.date.issued2014-05-20-
Data de envio: dc.date.issued2006-04-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1590/S1678-91992006000200010-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/26914-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/26914-
Descrição: dc.descriptionThe present work aimed to evaluate the clinical and hematological aspects during experimental envenomation by Crotalus durissus terrificus in dogs treated with different antiophidic serum doses. Sixteen dogs were divided into two groups of eight animals each. Group I received 1mg/kg venom subcutaneously and 30mg antiophidic serum intravenously; Group II received 1mg/kg venom subcutaneously and 60mg antiophidic serum intravenously. In the clinical evaluation, we observed ataxia, moderate sedation, dilated pupils, sialorrhea, flaccid paralysis of mandibular muscles, and discreet edema at the site of venom inoculation. Evaluating red and white blood cells, we observed a decrease of hemoglobins, globular volume and erythrocytes, and an increase of plasmatic proteins, leukocytes, neutrophils, monocytes and lymphocytes. Clotting time increased and there was blood incoagulability with return to normal clotting time six hours after antiophidic serum administration. Animals treated with six antiophidic serum flasks had a faster recovery than the animals that received three serum flasks.-
Formato: dc.format285-296-
Idioma: dc.languageen-
Publicador: dc.publisherUniversidade Estadual Paulista (UNESP), Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP)-
Relação: dc.relationJournal of Venomous Animals and Toxins Including Tropical Diseases-
Relação: dc.relation1.782-
Relação: dc.relation0,573-
Direitos: dc.rightsopenAccess-
Palavras-chave: dc.subjectCrotalus durissus terrificus-
Palavras-chave: dc.subjectdog-
Palavras-chave: dc.subjectclinical aspects-
Palavras-chave: dc.subjecthematological aspects-
Palavras-chave: dc.subjectvenom-
Título: dc.titleClinical and hematological alterations in dogs during experimental envenomation with Crotalus durissus terrificus venom and treated with antiophidic serum-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.