Smoking Intensity Increases Diaphragm Muscle Injury: A Clinicopathologic Study

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Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributor9 de Julho University—UNINOVE-
Autor(es): dc.contributorFaculty of Medicine of the ABC District-
Autor(es): dc.contributorDante Pazzanese Institute of Cardiology-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorNucci, Ricardo Aparecido Baptista-
Autor(es): dc.creatorBusse, Alexandre Leopold-
Autor(es): dc.creatorde Souza, Romeu Rodrigues-
Autor(es): dc.creatorMaifrino, Laura Beatriz Mesiano-
Autor(es): dc.creatorPasqualucci, Carlos Augusto-
Autor(es): dc.creatorAnaruma, Carlos Alberto-
Autor(es): dc.creatorLeite, Renata Elaine Paraizo-
Autor(es): dc.creatorRodriguez, Roberta Diehl-
Autor(es): dc.creatorSuemoto, Claudia Kimie-
Autor(es): dc.creatorJacob-Filho, Wilson-
Data de aceite: dc.date.accessioned2025-08-21T20:44:36Z-
Data de disponibilização: dc.date.available2025-08-21T20:44:36Z-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-06-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3390/jcm12113823-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/250050-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/250050-
Descrição: dc.descriptionBackground: Studying the effects of smoking intensity is important to evaluate the risk of tobacco use on a range of illnesses, such as as sarcopenia among the elderly. Thus, this study aimed to analyze the effects of pack-years of cigarette smoking on the diaphragm muscle (DIAm) histopathology of postmortem samples. Methods: Subjects were divided into three groups: never-smoker (n = 46); less than 30 pack-years of smoking (n = 12); and more than 30 pack-years of smoking (n = 30). Diaphragm samples were stained with Picrosirius red and hematoxylin and eosin stain for general structure. Results: Participants with more than 30 pack-years of cigarette smoking had a significant increase in adipocytes, blood vessels and collagen deposit, as well as an increase in histopathological alterations. Conclusions: Pack-years of smoking was associated with DIAm injury. However, further clinicopathological studies are needed to confirm our findings.-
Descrição: dc.descriptionDepartment of Pathology Faculty of Medicine University of São Paulo-
Descrição: dc.descriptionLaboratory of Medical Research in Aging (LIM-66) Division of Geriatrics Faculty of Medicine University of São Paulo-
Descrição: dc.descriptionDepartment of Anatomy Institute of Biomedical Sciences University of São Paulo-
Descrição: dc.descriptionDepartment of Anatomy 9 de Julho University—UNINOVE-
Descrição: dc.descriptionLaboratory of Clinical Analysis Faculty of Medicine of the ABC District-
Descrição: dc.descriptionDante Pazzanese Institute of Cardiology-
Descrição: dc.descriptionLaboratory of Morphology and Physical Activity Department of Physical Education São Paulo State University “Júlio de Mesquita Filho”-
Descrição: dc.descriptionLaboratory of Physiopathology in Aging (LIM-22) Department of Pathology Faculty of Medicine University of Sao Paulo-
Descrição: dc.descriptionLaboratory of Morphology and Physical Activity Department of Physical Education São Paulo State University “Júlio de Mesquita Filho”-
Idioma: dc.languageen-
Relação: dc.relationJournal of Clinical Medicine-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectautopsy-
Palavras-chave: dc.subjectcigarette-
Palavras-chave: dc.subjectdiaphragm-
Palavras-chave: dc.subjecthistopathology-
Título: dc.titleSmoking Intensity Increases Diaphragm Muscle Injury: A Clinicopathologic Study-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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