Antimicrobial behavior of titanium coating with chlorhexidine-doped thin film exposed to a biofilm supplemented with nicotine

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Autor(es): dc.contributorUniversity of Detroit Mercy-
Autor(es): dc.contributorUniversidade Estadual de Campinas (UNICAMP)-
Autor(es): dc.contributorIndiana University School of Dentistry-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorMatos, Adaias Oliveira-
Autor(es): dc.creatorRangel, Elidiane Cipriano-
Autor(es): dc.creatorBarão, Valentim Adelino Ricardo-
Autor(es): dc.creatorGregory, Richard Lee-
Data de aceite: dc.date.accessioned2025-08-21T19:47:06Z-
Data de disponibilização: dc.date.available2025-08-21T19:47:06Z-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2022-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.4012/dmj.2022-168-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/249808-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/249808-
Descrição: dc.descriptionBecause nicotine upregulates the growth of most oral bacteria, this in vitro study investigated the antimicrobial effect of chlorhexidine-doped thin film on commercially pure titanium against Fusobacterium nucleatum (F. nucleatum) biofilm supplemented with different concentrations of nicotine (0, 1, and 2 mg/mL). Biofilms were formed on a chlorhexidine-doped thin film on commercially-pure-titanium discs and compared to the control groups. Biofilm viability, total biofilm growth using a spectrophotometer, extracellular polysaccharide content, and pH variations were assessed as dependent variables. Data were submitted to ANOVA and Tukey honest significant difference tests (α=0.05). F. nucleatum biofilm growth was inhibited when exposed to chlorhexidine-doped thin film (p<0.05). Biofilm supplemented with nicotine did not impact the synthesis of EPS on the same type of treatment (p>0.05). The pH values were significantly increased with the increase of nicotine concentration (p<0.05). Chlorhexidine-doped thin film was effective in reducing F. nucleatum biofilm supplemented with nicotine.-
Descrição: dc.descriptionDivision of Clinical Essentials and Simulation University of Detroit Mercy-
Descrição: dc.descriptionDepartment of Prosthodontics and Periodontology Piracicaba Dental School University of Campinas (UNICAMP), Sao Paulo-
Descrição: dc.descriptionDepartment of Biomedical Sciences and Comprehensive Care Indiana University School of Dentistry-
Descrição: dc.descriptionLaboratory of Technological Plasmas (LaPTec) Engineering College Sao Paulo State University (UNESP), Sao Paulo-
Descrição: dc.descriptionLaboratory of Technological Plasmas (LaPTec) Engineering College Sao Paulo State University (UNESP), Sao Paulo-
Formato: dc.format228-235-
Idioma: dc.languageen-
Relação: dc.relationDental Materials Journal-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBiofilm-
Palavras-chave: dc.subjectChlorhexidine-
Palavras-chave: dc.subjectFusobacterium nucleatum-
Palavras-chave: dc.subjectNicotine-
Palavras-chave: dc.subjectTitanium-
Título: dc.titleAntimicrobial behavior of titanium coating with chlorhexidine-doped thin film exposed to a biofilm supplemented with nicotine-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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