Silver nanoparticles in denture adhesive: An antimicrobial approach against Candida albicans

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Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorPeralta, Laura Catalí Ferreira-
Autor(es): dc.creatorAlmeida, Nara Ligia Martins-
Autor(es): dc.creatorPontes, Fenelon Martinho Lima-
Autor(es): dc.creatorRinaldo, Daniel-
Autor(es): dc.creatorCarneiro, Camila Alves-
Autor(es): dc.creatorNeppelenbroek, Karin Hermana-
Autor(es): dc.creatorLara, Vanessa Soares-
Autor(es): dc.creatorPorto, Vinicius Carvalho-
Data de aceite: dc.date.accessioned2025-08-21T17:09:59Z-
Data de disponibilização: dc.date.available2025-08-21T17:09:59Z-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-04-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.jdent.2023.104445-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/249687-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/249687-
Descrição: dc.descriptionObjective: To evaluate the antimicrobial potential of silver nanoparticles (Ag NPs) synthesized using three different routes (ultraviolet light, Turkevich, and green chemistry method using Glycine max extract) associated with COREGA® denture powder adhesive. Methods: Heat-cured acrylic resin specimens were treated with different Ag NPs associated with the adhesive (AD + Ag UV, AD + Ag Turk, and AD + Ag Gm groups). As controls, the specimens were treated with a combination of adhesive and nystatin (AD + Nyst group), only adhesive (AD group), or submerged on the surface of the specimens (PBS group). After the treatments, biofilms of C. albicans developed for 3, 6, and 12 h on the specimen surfaces. The biofilm was quantified using colony-forming units per milliliter, colorimetric assay, and confocal laser scanning microscopy. Results: Regardless of the period, we observed an inhibition of fungal load and a reduction in metabolic activity and biofilm mass in the resin specimens treated with the combinations AD/Ag NPs, compared to AD and PBS. The antimicrobial action of the AD + Turk and AD + Ag Gm groups was similar than that for the AD + Nyst group in all periods and viability tests, except for the biofilm mass (12 h). Conclusions: The COREGA® adhesive with Ag NPs, mainly those synthesized using the Turkevich and Glycine max methods, showed excellent antimicrobial activity against C. albicans biofilms, maintained for up to 12 h. Clinical significance: The association of Ag NPs to the adhesive can add preventive or therapeutic effects against denture stomatitis, to this prosthetic material.-
Descrição: dc.descriptionDepartment of Prosthodontics and Periodontics Bauru School of Dentistry University of São Paulo (USP)-
Descrição: dc.descriptionDepartment of Surgery Stomatology Pathology and Radiology Bauru School of Dentistry University of São Paulo (USP)-
Descrição: dc.descriptionDepartment of Chemistry São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Chemistry São Paulo State University (UNESP)-
Idioma: dc.languageen-
Relação: dc.relationJournal of Dentistry-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAntimicrobial agents-
Palavras-chave: dc.subjectCandida albicans-
Palavras-chave: dc.subjectDenture stomatitis-
Palavras-chave: dc.subjectNanotechnology-
Palavras-chave: dc.subjectSilver nanoparticles-
Palavras-chave: dc.subjectTissue adhesives-
Título: dc.titleSilver nanoparticles in denture adhesive: An antimicrobial approach against Candida albicans-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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