A new approach for professional dental bleaching using a polymeric catalyst primer

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorDias, Marlon Ferreira-
Autor(es): dc.creatorMartins, Beatriz Voss-
Autor(es): dc.creatorde Oliveira Ribeiro, Rafael Antonio-
Autor(es): dc.creatorLeite, Maria Luísa-
Autor(es): dc.creatorOrtecho-Zuta, Uxua-
Autor(es): dc.creatorHebling, Josimeri-
Autor(es): dc.creatorCosta, Carlos Alberto de Souza-
Data de aceite: dc.date.accessioned2025-08-21T20:43:07Z-
Data de disponibilização: dc.date.available2025-08-21T20:43:07Z-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-03-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1111/jerd.12972-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/249222-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/249222-
Descrição: dc.descriptionObjective: Evaluate the influence of a polymeric catalyst primer (PCP) on esthetic efficacy (EE), degradation kinetics of hydrogen peroxide (H2O2), and trans-amelodentinal cytotoxicity (TC) of bleaching gels. Materials and Methods: The following groups were established: G1: No treatment (NC, negative control); G2: PCP; G3: 10% H2O2; G4: PCP + 10% H2O2; G5: 20% H2O2; G6: PCP + 20% H2O2; G7: 35% H2O2 (positive control); G8: PCP + 35% H2O2. To determine EE, enamel/dentin discs (E/DDs) were stained and subjected or not to bleaching protocols for 45 min. To assess TC, the E/DDs were adapted to artificial pulp chambers. The extracts (culture medium + gel components diffused through E/DDs) were applied to odontoblast-like MDPC-23 cells. The viability (VB), oxidative stress (OxS), morphology (SEM), amount of H2O2 diffused and the production of hydroxyl radical (OH•) were assessed (two-way ANOVA/Tukey/paired Student t-test; p < 0.05). Results: The highest EE was found in G8 (p < 0.05), and G4, G6, and G7 did not differ statistically (p > 0.05). In G4, the limited H2O2 diffusion reduced OxS and increased cell VB (p < 0.05). Conclusions: Coating the enamel with PCP containing 10 mg/ml of manganese oxide before applying the 10% H2O2 bleaching gel maintains the EE of conventional in-office bleaching and minimizes the toxic effects of this esthetic therapy. Clinical Significance: Coating the enamel with a PCP before applying the bleaching gel may potentiate the EE of the conventional in-office tooth bleaching and reduce the toxicity of this professional therapy to the dental pulp.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionDepartment of Dental Materials and Prosthodontics School of Dentistry São Paulo State University-
Descrição: dc.descriptionDepartment of Morphology Genetics Orthodontics and Pediatric Dentistry School of Dentistry São Paulo State University-
Descrição: dc.descriptionDepartment of Physiology and Pathology School of Dentistry São Paulo State University-
Descrição: dc.descriptionDepartment of Dental Materials and Prosthodontics School of Dentistry São Paulo State University-
Descrição: dc.descriptionDepartment of Morphology Genetics Orthodontics and Pediatric Dentistry School of Dentistry São Paulo State University-
Descrição: dc.descriptionDepartment of Physiology and Pathology School of Dentistry São Paulo State University-
Descrição: dc.descriptionFAPESP: 2020/08882-6-
Descrição: dc.descriptionCNPq: 302047/2019-0-
Descrição: dc.descriptionCNPq: 408721/2018-9-
Descrição: dc.descriptionCAPES: Finance Code 001-
Formato: dc.format406-415-
Idioma: dc.languageen-
Relação: dc.relationJournal of Esthetic and Restorative Dentistry-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectcolor science-
Palavras-chave: dc.subjectdental materials-
Palavras-chave: dc.subjectodontoblasts-
Palavras-chave: dc.subjecttooth bleaching-
Palavras-chave: dc.subjecttoxicity-
Título: dc.titleA new approach for professional dental bleaching using a polymeric catalyst primer-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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