Analysis of the biocompatibility of a biocelulose and a poly L-lactic acid membrane

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Autor(es): dc.contributorAraraquara University Center (UNIARA)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorUniversidade Federal de Uberlândia (UFU)-
Autor(es): dc.creatorNeto, José Doval-
Autor(es): dc.creatorMarques, Rodrigo Fernando Costa-
Autor(es): dc.creatorMotta, Adriana Cristina-
Autor(es): dc.creatorde Rezende Duek, Eliana Aparecida-
Autor(es): dc.creatorde Oliveira, Guilherme José Pimentel Lopes-
Autor(es): dc.creatorMarcantonio, Cláudio-
Data de aceite: dc.date.accessioned2025-08-21T20:10:17Z-
Data de disponibilização: dc.date.available2025-08-21T20:10:17Z-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2020-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.20396/BJOS.V21I00.8670616-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/249195-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/249195-
Descrição: dc.descriptionThe use of selective barriers as resorbable membranes has become a routine clinical procedure for guided bone regeneration. Therefore, the production of membranes with a low inflammatory potential during their resorption process has become the goal of a considerable number of researches. Aim: The purpose of the present study was to evaluate the biocompatibility of poly (L-lactic acid) (PLLA) and biocelulose membranes (BC) inserted in the subcutaneous tissue on the dorsum of rats. Methods: Fifteen animals underwent surgical procedures for the insertion of 4 types of membranes: COL (Collagen membrane) – Control Group; BC (Biocellulose membrane); BCAg (Biocellulose membrane impregnated with Silver); PLLA (Poly (L-lactic acid) membrane). All membrane types were inserted into each animal. Animals were euthanized after 3, 7, and 15 days of the surgical procedure. Descriptive histological analyses were carried out to investigate host tissue reaction to membrane presence by assessing the anti-inflammatory process composition associated with the membrane resorption and the presence of foreign-body reaction or encapsulation. Results: The BC membranes showed a higher degree of inflammation and poor pattern of integration with the surrounding tissues than the PLLA and COL membranes. Conclusion: The PLLA and COL membranes present better biocompatibility than the BC membranes.-
Descrição: dc.descriptionAraraquara Dental School Department of Postgraduate Studies in Implantology Araraquara University Center (UNIARA)-
Descrição: dc.descriptionInstitute of Chemistry Paulista State University-
Descrição: dc.descriptionBiomaterials Laboratory Faculty of Medical Sciences and Health Pontifical Catholic University of São Paulo-
Descrição: dc.descriptionDepartment of Periodontology/ Implantodontology School of Dentistry Federal University of Uberlândia (UFU)-
Descrição: dc.descriptionInstitute of Chemistry Paulista State University-
Idioma: dc.languageen-
Relação: dc.relationBrazilian Journal of Oral Sciences-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBiocompatible materials-
Palavras-chave: dc.subjectCelulose-
Palavras-chave: dc.subjectInflammation-
Palavras-chave: dc.subjectMembranes-
Palavras-chave: dc.subjectPolyesters-
Título: dc.titleAnalysis of the biocompatibility of a biocelulose and a poly L-lactic acid membrane-
Tipo de arquivo: dc.typelivro digital-
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