Antimicrobial metabolites produced by endophytic fungi associated with the leaves of Vochysia divergens

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorFederal University of Mato Grosso-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorMilitary College of Campo Grande-
Autor(es): dc.contributorFederal University of Mato Grosso do Sul-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorFederal University of Rondonópolis-
Autor(es): dc.contributorFederal University of Amazonas-
Autor(es): dc.contributorFederal University of Grande Dourados-
Autor(es): dc.contributorUniversidade Federal de São Carlos (UFSCar)-
Autor(es): dc.creatorSouza, Jéssica A. de M.-
Autor(es): dc.creatorGubiani, Juliana R.-
Autor(es): dc.creatorde Siqueira, Kátia A.-
Autor(es): dc.creatorde Camargo, Maria J.-
Autor(es): dc.creatorGarcez, Walmir S.-
Autor(es): dc.creatorde Sousa, Paulo T.-
Autor(es): dc.creatorSoares, Marcos A.-
Autor(es): dc.creatorAraújo, Ângela R.-
Autor(es): dc.creatorNunes, Emanuel V. dos S.-
Autor(es): dc.creatorVieira, Lucas C. C.-
Autor(es): dc.creatorSampaio, Olívia M.-
Autor(es): dc.creatorGoulart, Letícia S.-
Autor(es): dc.creatorBiasetto, Carolina R.-
Autor(es): dc.creatorde Menezes, Orivaldo T.-
Autor(es): dc.creatorde Oliveira, Camila M.-
Autor(es): dc.creatorNogueira, Cláudio R.-
Autor(es): dc.creatorPinto, Luciano da S.-
Autor(es): dc.creatorTeles, Helder L.-
Data de aceite: dc.date.accessioned2025-08-21T22:57:37Z-
Data de disponibilização: dc.date.available2025-08-21T22:57:37Z-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2022-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1080/14786419.2023.2208723-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/248790-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/248790-
Descrição: dc.descriptionInvestigation of the endophytic fungi Nigrospora sphaerica, Nigrospora oryzae, and Pseudofusicoccum stromaticum MeOH fractions isolated from the leaves of Vochysia divergens, a medicinal species from the Brazilian Pantanal, led to the identification of five compounds, namely a new compound (1E,8Z)-10,11-dihydroxy-5,5,8-trimethyl-4-oxocycloundeca-1,8-diene-1-carbaldehyde (1) and four known compounds: 5-methylmellein (2), sclerone (3), daldinone A (4), and lasiodiplodin (5). All compounds were identified using spectroscopic methods, and 1 was corroborated with mass spectrometry, while the known compounds were compared with data in the literature. The relative configuration of compound 1 was determined based on theoretical conformational studies as well as the J experimental values between the hydroxymethyne hydrogens. The antimicrobial activity of the compounds was evaluated. Promising results were obtained for compounds 2, 4, and 5 since they inhibited the bacterium Pseudomonas aeruginosa, an opportunistic pathogen, suggesting the potential of these microorganisms as a source of new antibacterial agents.-
Descrição: dc.descriptionDepartment of Chemistry Federal University of Mato Grosso-
Descrição: dc.descriptionInstitute of Chemistry of São Carlos São Paulo University-
Descrição: dc.descriptionInstitute of Biosciences Federal University of Mato Grosso-
Descrição: dc.descriptionMilitary College of Campo Grande-
Descrição: dc.descriptionInstitute of Chemistry Federal University of Mato Grosso do Sul-
Descrição: dc.descriptionInstitute of Chemistry Department of Biochemistry and Organic Chemistry NuBBE São Paulo State University-
Descrição: dc.descriptionFaculty of Health Sciences Federal University of Rondonópolis-
Descrição: dc.descriptionInstitute of Exact Sciences and Technology Federal University of Amazonas-
Descrição: dc.descriptionInstitute of Exact and Natural Sciences Federal University of Rondonópolis-
Descrição: dc.descriptionFaculty of Exact Sciences and Technology Federal University of Grande Dourados-
Descrição: dc.descriptionDepartment of Chemistry Federal University of São Carlos-
Descrição: dc.descriptionInstitute of Chemistry Department of Biochemistry and Organic Chemistry NuBBE São Paulo State University-
Idioma: dc.languageen-
Relação: dc.relationNatural Product Research-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectantibacterial activity-
Palavras-chave: dc.subjectEndophytic fungi-
Palavras-chave: dc.subjectVochysia divergens-
Título: dc.titleAntimicrobial metabolites produced by endophytic fungi associated with the leaves of Vochysia divergens-
Tipo de arquivo: dc.typelivro digital-
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