Lymphomatoid Papulosis Type E Affecting the Palate: A Detailed Case Report and Review of Literature

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.creatorSilveira, Heitor Albergoni-
Autor(es): dc.creatorRagusa Silva, Paula Verona-
Autor(es): dc.creatorPimentel, Bruna Gonçalves-
Autor(es): dc.creatorNogueira, Gustavo Milhomens-
Autor(es): dc.creatorChahud, Fernando-
Autor(es): dc.creatorBrunaldi, Mariângela Ottoboni-
Autor(es): dc.creatorLeón, Jorge Esquiche-
Data de aceite: dc.date.accessioned2025-08-21T18:39:48Z-
Data de disponibilização: dc.date.available2025-08-21T18:39:48Z-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-05-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1097/DAD.0000000000002405-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/248718-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/248718-
Descrição: dc.descriptionLymphomatoid papulosis (LyP) belongs to the spectrum of primary cutaneous CD30+lymphoproliferative disorders, characterized by chronic, recurrent, self-healing papules, small nodules, or ulcers. The clinicopathological features of LyP can mimic overt lymphomas. To date, about 27 intraoral LyP cases have been reported. Of them, only 2 cases were diagnosed as angioinvasive LyP (type E). Herein, we report a 24-year-old Brazilian man who presented a large ulcerated lesion on the hard palate with rapid evolution. Remarkably, there was no involvement of the skin or other mucous membranes. Microscopy revealed a lymphoid infiltrate constituted by medium-sized to large atypical cells, with angiocentric and angiodestructive features. The atypical cells showed immunopositivity for CD3, CD8, CD30, CD56, granzyme B, perforin, and focally for MUM1/IRF4. Ki-67 highlighted almost all atypical lymphoid cells, whereas EBER1/2 was negative. After 2 months of follow-up, the lesion healed completely. Although rare, LyP type E should be included in the differential diagnosis of oral ulcers.-
Descrição: dc.descriptionOral Medicine Department of Diagnosis and Surgery Araraquara Dental School São Paulo State University (UNESP)-
Descrição: dc.descriptionOral Pathology Department of Stomatology Public Oral Health and Forensic Dentistry Ribeirão Preto Dental School (FORP/USP) University of São Paulo, Ribeirão Preto-
Descrição: dc.descriptionDepartment of Pathology and Forensic Medicine Ribeirão Preto Medical School (FMRP/USP) University of São Paulo, Ribeirão Preto-
Descrição: dc.descriptionOral Medicine Department of Diagnosis and Surgery Araraquara Dental School São Paulo State University (UNESP)-
Formato: dc.format326-329-
Idioma: dc.languageen-
Relação: dc.relationAmerican Journal of Dermatopathology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectangioinvasive-
Palavras-chave: dc.subjectdifferential diagnosis-
Palavras-chave: dc.subjectlymphoma-
Palavras-chave: dc.subjectlymphomatoid papulosis type E-
Palavras-chave: dc.subjectlymphoproliferative disorder-
Palavras-chave: dc.subjectoral cavity-
Título: dc.titleLymphomatoid Papulosis Type E Affecting the Palate: A Detailed Case Report and Review of Literature-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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