Consequences of the exposome to gestational diabetes mellitus

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorPravara Institute of Medical Sciences (DU)-
Autor(es): dc.contributorImperial College London-
Autor(es): dc.contributorUniversity Medical Center Groningen-
Autor(es): dc.contributorUniversidad de Talca-
Autor(es): dc.contributorUniversidad de Antofagasta-
Autor(es): dc.contributorUniversidad del Bío-Bío-
Autor(es): dc.contributorSchool of Medicine and Health Sciences-
Autor(es): dc.contributorUniversidad de Sevilla-
Autor(es): dc.contributorUniversity of Queensland-
Autor(es): dc.contributorPontificia Universidad Católica de Chile-
Autor(es): dc.creatorRudge, Marilza V.C.-
Autor(es): dc.creatorAlves, Fernanda C.B.-
Autor(es): dc.creatorHallur, Raghavendra L.S.-
Autor(es): dc.creatorOliveira, Rafael G.-
Autor(es): dc.creatorVega, Sofia-
Autor(es): dc.creatorReyes, David R.A.-
Autor(es): dc.creatorFloriano, Juliana F.-
Autor(es): dc.creatorPrudencio, Caroline B.-
Autor(es): dc.creatorGarcia, Gabriela A.-
Autor(es): dc.creatorReis, Fabiana V.D.S.-
Autor(es): dc.creatorEmanueli, Costanza-
Autor(es): dc.creatorFuentes, Gonzalo-
Autor(es): dc.creatorCornejo, Marcelo-
Autor(es): dc.creatorToledo, Fernando-
Autor(es): dc.creatorValenzuela-Hinrichsen, Andrés-
Autor(es): dc.creatorGuerra, Catalina-
Autor(es): dc.creatorGrismaldo, Adriana-
Autor(es): dc.creatorValero, Paola-
Autor(es): dc.creatorBarbosa, Angelica M.P.-
Autor(es): dc.creatorSobrevia, Luis-
Data de aceite: dc.date.accessioned2025-08-21T15:35:00Z-
Data de disponibilização: dc.date.available2025-08-21T15:35:00Z-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-01-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.bbagen.2022.130282-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/247966-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/247966-
Descrição: dc.descriptionThe exposome is the cumulative measure of environmental influences and associated biological responses throughout the lifespan, including those from the environment, diet, behaviour, and endogenous processes. The exposome concept and the 2030 Agenda for the Sustainable Development Goals (SDGs) from the United Nations are the basis for understanding the aetiology and consequences of non-communicable diseases, including gestational diabetes mellitus (GDM). Pregnancy may be developed in an environment with adverse factors part of the immediate internal medium for fetus development and the external medium to which the pregnant woman is exposed. The placenta is the interface between maternal and fetal compartments and acts as a protective barrier or easing agent to transfer exposome from mother to fetus. Under and over-nutrition in utero, exposure to adverse environmental pollutants such as heavy metals, endocrine-disrupting chemicals, pesticides, drugs, pharmaceuticals, lifestyle, air pollutants, and tobacco smoke plays a determinant role in the development of GDM. This phenomenon is worsened by metabolic stress postnatally, such as obesity which increases the risk of GDM and other diseases. Clinical risk factors for GDM development include its aetiology. It is proposed that knowledge-based interventions to change the potential interdependent ecto-exposome and endo-exposome could avoid the occurrence and consequences of GDM.-
Descrição: dc.descriptionRijksuniversiteit Groningen-
Descrição: dc.descriptionPontificia Universidad Católica de Chile-
Descrição: dc.descriptionFondo Nacional de Desarrollo Científico y Tecnológico-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionDepartment of Gynaecology and Obstetrics Botucatu Medical School São Paulo State University (UNESP), São Paulo-
Descrição: dc.descriptionCentre for Biotechnology Pravara Institute of Medical Sciences (DU), Loni-413736, Rahata Taluk, Ahmednagar District-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Sciences Postgraduate Program in Materials Science and Technology (POSMAT), São Paulo-
Descrição: dc.descriptionNational Heart and Lung Institute Imperial College London-
Descrição: dc.descriptionDepartment of Pathology and Medical Biology University of Groningen University Medical Center Groningen-
Descrição: dc.descriptionFaculty of Health Sciences Universidad de Talca-
Descrição: dc.descriptionFaculty of Health Sciences Universidad de Antofagasta-
Descrição: dc.descriptionFaculty of Basic Sciences Universidad del Bío-Bío-
Descrição: dc.descriptionDepartment of Physiotherapy and Occupational Therapy School of Philosophy and Sciences São Paulo State University (UNESP), São Paulo-
Descrição: dc.descriptionTecnologico de Monterrey Eutra The Institute for Obesity Research (IOR) School of Medicine and Health Sciences, Nuevo León-
Descrição: dc.descriptionDepartment of Physiology Faculty of Pharmacy Universidad de Sevilla-
Descrição: dc.descriptionUniversity of Queensland Centre for Clinical Research (UQCCR) Faculty of Medicine and Biomedical Sciences University of Queensland-
Descrição: dc.descriptionCellular and Molecular Physiology Laboratory (CMPL) Department of Obstetrician Division of Obstetrics and Gynaecology School of Medicine Faculty of Medicine Pontificia Universidad Católica de Chile-
Descrição: dc.descriptionDepartment of Gynaecology and Obstetrics Botucatu Medical School São Paulo State University (UNESP), São Paulo-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Sciences Postgraduate Program in Materials Science and Technology (POSMAT), São Paulo-
Descrição: dc.descriptionDepartment of Physiotherapy and Occupational Therapy School of Philosophy and Sciences São Paulo State University (UNESP), São Paulo-
Descrição: dc.descriptionFondo Nacional de Desarrollo Científico y Tecnológico: 1190316-
Descrição: dc.descriptionFAPESP: 16/01743-5-
Descrição: dc.descriptionCNPq: 305116/2018-5-
Idioma: dc.languageen-
Relação: dc.relationBiochimica et Biophysica Acta - General Subjects-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectbiomarkers-
Palavras-chave: dc.subjectendogenous exposomes-
Palavras-chave: dc.subjectenvironmental exposures-
Palavras-chave: dc.subjectexposome-
Palavras-chave: dc.subjectgestational diabetes-
Título: dc.titleConsequences of the exposome to gestational diabetes mellitus-
Tipo de arquivo: dc.typevídeo-
Aparece nas coleções:Repositório Institucional - Unesp

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