Impact of the COVID-19 Pandemic on Solid Organ Transplant and Rejection Episodes in Brazil’s Unified Healthcare System

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorHealth Technology Assessment Center Hospital das Clínicas—HCFMB-
Autor(es): dc.contributorTransplant Unit—Santa Casa Juiz de Fora-
Autor(es): dc.creatorde Andrade, Luis Gustavo Modelli-
Autor(es): dc.creatorBarbosa, Abner Macola Pacheco-
Autor(es): dc.creatorda Rocha, Naila Camila-
Autor(es): dc.creatorde Almeida Cardoso, Marilia Mastrocolla-
Autor(es): dc.creatorde Almeida, Juliana Tereza Coneglian-
Autor(es): dc.creatorMachado-Rugolo, Juliana-
Autor(es): dc.creatorArantes, Lucas Frederico-
Autor(es): dc.creatorPontes, Daniela Ferreira Salomão-
Autor(es): dc.creatorFerreira, Gustavo Fernandes-
Data de aceite: dc.date.accessioned2025-08-21T17:52:51Z-
Data de disponibilização: dc.date.available2025-08-21T17:52:51Z-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2022-10-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3390/jcm11216581-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/247854-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/247854-
Descrição: dc.descriptionBackground: Brazil has the world’s largest public organ transplant program, which was severely affected by the COVID-19 pandemic. The primary aim of the study was to evaluate differences in solid organ transplants and rejection episodes during the COVID-19 pandemic compared to the five years before the pandemic in the country. Methods: A seven-year database was built by downloading data from the DATASUS server. The pandemic period was defined as March 2020 to December 2021. The pre-pandemic period was from January 2015 to March 2020. Results: During the pandemic, the number of solid organ transplants decreased by 19.3% in 2020 and 22.6% in 2021 compared to 2019. We found a decrease for each evaluated organ, which was more pronounced for lung, pancreas, and kidney transplants. The seasonal plot of rejection data indicated a high rejection rate between 2018 and 2021. There was also an 18% (IRR 1.18 (95% CI 1.01 to 1.37), p = 0.04) increase in the rejection rate during the COVID-19 pandemic. Conclusions: The total number of organ transplants performed in 2021 represents a setback of six years. Transplant procedures were concentrated in the Southeast region of the country, and a higher proportion of rejections occurred during the pandemic. Together, these findings could have an impact on transplant procedures and outcomes in Brazil.-
Descrição: dc.descriptionDepartment of Internal Medicine—UNESP Univ Estadual Paulista, Av. Prof. Montenegro—Distrito de, Rubião Jr., s/n, SP-
Descrição: dc.descriptionHealth Technology Assessment Center Hospital das Clínicas—HCFMB, SP-
Descrição: dc.descriptionTransplant Unit—Santa Casa Juiz de Fora, Av. Barão do Rio Branco, 3353-Passos, MG-
Descrição: dc.descriptionDepartment of Internal Medicine—UNESP Univ Estadual Paulista, Av. Prof. Montenegro—Distrito de, Rubião Jr., s/n, SP-
Idioma: dc.languageen-
Relação: dc.relationJournal of Clinical Medicine-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBrazil-
Palavras-chave: dc.subjectCOVID-19-
Palavras-chave: dc.subjectgraft rejection-
Palavras-chave: dc.subjectorgan transplant-
Título: dc.titleImpact of the COVID-19 Pandemic on Solid Organ Transplant and Rejection Episodes in Brazil’s Unified Healthcare System-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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