Risk Factors Associated with Mortality in Hospitalized Patients with COVID-19 during the Omicron Wave in Brazil

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorImmunization Division—Centre of Epidemiology Surveillance of the São Paulo State Health Department-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.creatorColnago, Marilaine-
Autor(es): dc.creatorBenvenuto, Giovana A.-
Autor(es): dc.creatorCasaca, Wallace-
Autor(es): dc.creatorNegri, Rogério G.-
Autor(es): dc.creatorFernandes, Eder G.-
Autor(es): dc.creatorCuminato, José A.-
Data de aceite: dc.date.accessioned2025-08-21T21:03:20Z-
Data de disponibilização: dc.date.available2025-08-21T21:03:20Z-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2022-10-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3390/bioengineering9100584-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/247783-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/247783-
Descrição: dc.descriptionConsidering the imminence of new SARS-CoV-2 variants and COVID-19 vaccine availability, it is essential to understand the impact of the disease on the most vulnerable groups and those at risk of death from the disease. To this end, the odds ratio (OR) for mortality and hospitalization was calculated for different groups of patients by applying an adjusted logistic regression model based on the following variables of interest: gender, booster vaccination, age group, and comorbidity occurrence. A massive number of data were extracted and compiled from official Brazilian government resources, which include all reported cases of hospitalizations and deaths associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Brazil during the “wave” of the Omicron variant (BA.1 substrain). Males (1.242; 95% CI 1.196–1.290) aged 60–79 (3.348; 95% CI 3.050–3.674) and 80 years or older (5.453; 95% CI 4.966–5.989), and hospitalized patients with comorbidities (1.418; 95% CI 1.355–1.483), were more likely to die. There was a reduction in the risk of death (0.907; 95% CI 0.866–0.951) among patients who had received the third dose of the anti-SARS-CoV-2 vaccine (booster). Additionally, this big data investigation has found statistical evidence that vaccination can support mitigation plans concerning the current scenario of COVID-19 in Brazil since the Omicron variant and its substrains are now prevalent across the entire country.-
Descrição: dc.descriptionInstitute of Chemistry São Paulo State University (UNESP)-
Descrição: dc.descriptionFaculty of Science and Technology (FCT) São Paulo State University (UNESP)-
Descrição: dc.descriptionInstitute of Biosciences Letters and Exact Sciences São Paulo State University (UNESP)-
Descrição: dc.descriptionScience and Technology Institute São Paulo State University (UNESP)-
Descrição: dc.descriptionImmunization Division—Centre of Epidemiology Surveillance of the São Paulo State Health Department-
Descrição: dc.descriptionInstitute of Mathematics and Computer Science São Paulo University (USP)-
Descrição: dc.descriptionInstitute of Chemistry São Paulo State University (UNESP)-
Descrição: dc.descriptionFaculty of Science and Technology (FCT) São Paulo State University (UNESP)-
Descrição: dc.descriptionInstitute of Biosciences Letters and Exact Sciences São Paulo State University (UNESP)-
Descrição: dc.descriptionScience and Technology Institute São Paulo State University (UNESP)-
Idioma: dc.languageen-
Relação: dc.relationBioengineering-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCOVID-19-
Palavras-chave: dc.subjecthospitalization-
Palavras-chave: dc.subjectmortality-
Palavras-chave: dc.subjectOmicron-
Palavras-chave: dc.subjectrisk factors-
Título: dc.titleRisk Factors Associated with Mortality in Hospitalized Patients with COVID-19 during the Omicron Wave in Brazil-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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