Evaluation of tooth eruption rate of incisor teeth in rats with estrogen deficiency

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorCidade Universitária-
Autor(es): dc.contributorUniversidade Estadual de Campinas (UNICAMP)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversity of the Joinville Region-
Autor(es): dc.contributorUniversity Medical Centre of Regensburg-
Autor(es): dc.creatorMadalena, Isabela Ribeiro-
Autor(es): dc.creatorMarañón-Vásquez, Guido Artemio-
Autor(es): dc.creatorOmori, Marjorie Ayumi-
Autor(es): dc.creatorde Sousa, Emerson Tavares-
Autor(es): dc.creatorda Silveira, Heitor Albergoni-
Autor(es): dc.creatorLeón, Jorge Esquiche-
Autor(es): dc.creatorBaratto-Filho, Flares-
Autor(es): dc.creatorAlves, Sandra Yasuyo Fukada-
Autor(es): dc.creatorStuani, Maria Bernadete Sasso-
Autor(es): dc.creatorNelson-Filho, Paulo-
Autor(es): dc.creatorKirschneck, Christian-
Autor(es): dc.creatorKüchler, Erika Calvano-
Data de aceite: dc.date.accessioned2025-08-21T21:52:47Z-
Data de disponibilização: dc.date.available2025-08-21T21:52:47Z-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2022-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s00784-022-04738-w-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/247757-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/247757-
Descrição: dc.descriptionObjectives: To assess the influence of estrogen deficiency on tooth eruption rate (TER) and gene expression of estrogen receptor alpha and beta (ERα and ERβ) in the odontogenic region of teeth with continuous formation in a rat model. Materials and methods: Ovariectomies (OVX; n = 25) and sham surgeries (SHAM; n = 25) were performed in female Wistar rats when animals were 25 days old. The TER of the lower incisors, both in impeded (hyperfunction condition) and unimpeded (trimmed incisal edge—hypofunction condition) conditions, was evaluated using standardized digital photographs acquired every 48–72 h for 3 weeks (35th–53rd day of life), using a camera coupled to a stereomicroscope. Quantitative real-time PCR was performed to evaluate the relative gene expression of ERα and ERβ in the odontogenic region. Results: The OVX group showed a significant reduction in TER when compared to the SHAM group, only in the impeded condition (p = 0.03). There was no statistically significant difference between the groups in ERα gene expression (p = 0.33). ERβ showed a significantly higher gene expression in the OVX group (p ≤ 0.05). Conclusions: Estrogen deficiency decreases TER in teeth under impeded condition. Estrogen deficiency also increases ERβ gene expression in the odontogenic region of teeth with continuous formation. Clinical relevance: Hormonal disturbances affecting estrogen levels can cause alterations in dental formation and teeth eruption.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionAlexander von Humboldt-Stiftung-
Descrição: dc.descriptionDepartment of Pediatric Dentistry School of Dentistry of Ribeirão Preto University of São Paulo Avenida Do Café S/N, Campus da USP, SP-
Descrição: dc.descriptionDepartment of Pediatric Dentistry and Orthodontics School of Dentistry Federal University of Rio de Janeiro Cidade Universitária, Rua Prof. Rodolpho Paulo Rocco 325, RJ-
Descrição: dc.descriptionDepartment of Health Sciences and Pediatric Dentistry Piracicaba Dental School University of Campinas, Avenida Limeira 901, SP-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery Araraquara Dental School São Paulo State University, Rua Humaitá, CentroSP-
Descrição: dc.descriptionDepartment of Stomatology Public Health and Forensic Dentistry School of Dentistry of Ribeirão Preto University of São Paulo Avenida Do Café S/N, Campus da USP, SP-
Descrição: dc.descriptionSchool of Dentistry University of the Joinville Region, Rua Paulo Malschitzki, s/n, SC-
Descrição: dc.descriptionDepartment of Biomolecular Sciences School of Pharmaceutical Sciences of Ribeirão Preto University of São Paulo Avenida Do Café S/N, Campus da USP, SP-
Descrição: dc.descriptionDepartment of Orthodontics University Medical Centre of Regensburg, Franz-Josef-Strauss-Allee 11-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery Araraquara Dental School São Paulo State University, Rua Humaitá, CentroSP-
Descrição: dc.descriptionCAPES: 001-
Descrição: dc.descriptionFAPESP: 2015/06866-5-
Descrição: dc.descriptionFAPESP: 2016/08149-1-
Descrição: dc.descriptionAlexander von Humboldt-Stiftung: Küchler/Kirschneck 04th july 2019-
Formato: dc.format345-352-
Idioma: dc.languageen-
Relação: dc.relationClinical Oral Investigations-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectEstrogen receptor alpha-
Palavras-chave: dc.subjectEstrogen receptor beta-
Palavras-chave: dc.subjectEstrogens-
Palavras-chave: dc.subjectOdontogenesis-
Palavras-chave: dc.subjectTooth eruption-
Título: dc.titleEvaluation of tooth eruption rate of incisor teeth in rats with estrogen deficiency-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.