Untargeted metabolomics approach and molecular networking analysis reveal changes in chemical composition under the influence of altitudinal variation in bamboo species

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorPontificia Universidad Javeriana-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidad Nacional de Colombia-
Autor(es): dc.contributorUniversidad de los Andes-
Autor(es): dc.contributorUniversidad de Guadalajara-
Autor(es): dc.creatorChitiva, Luis Carlos-
Autor(es): dc.creatorLozano-Puentes, Hair Santiago-
Autor(es): dc.creatorLondoño, Ximena-
Autor(es): dc.creatorLeão, Tiago F.-
Autor(es): dc.creatorCala, Mónica P.-
Autor(es): dc.creatorRuiz-Sanchez, Eduardo-
Autor(es): dc.creatorDíaz-Ariza, Lucía Ana-
Autor(es): dc.creatorPrieto-Rodríguez, Juliet A.-
Autor(es): dc.creatorCastro-Gamboa, Ian-
Autor(es): dc.creatorCosta, Geison M.-
Data de aceite: dc.date.accessioned2025-08-21T18:04:54Z-
Data de disponibilização: dc.date.available2025-08-21T18:04:54Z-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2022-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3389/fmolb.2023.1192088-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/247551-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/247551-
Descrição: dc.descriptionBamboo species have traditionally been used as building material and potential source of bioactive substances, as they produce a wide variety of phenolic compounds, including flavonoids and cinnamic acid derivatives that are considered biologically active. However, the effects of growth conditions such as location, altitude, climate, and soil on the metabolome of these species still need to be fully understood. This study aimed to evaluate variations in chemical composition induced by altitudinal gradient (0–3000 m) by utilizing an untargeted metabolomics approach and mapping chemical space using molecular networking analysis. We analyzed 111 samples from 12 bamboo species collected from different altitudinal ranges using liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (LC-QTOF-MS). We used multivariate and univariate statistical analyses to identify the metabolites that showed significant differences in the altitude environments. Additionally, we used the Global Natural Products Social Molecular Networking (GNPS) web platform to perform chemical mapping by comparing the metabolome among the studied species and the reference spectra from its database. The results showed 89 differential metabolites between the altitudinal ranges investigated, wherein high altitude environments significantly increased the profile of flavonoids. While, low altitude environments significantly boosted the profile of cinnamic acid derivatives, particularly caffeoylquinic acids (CQAs). MolNetEnhancer networks confirmed the same differential molecular families already found, revealing metabolic diversity. Overall, this study provides the first report of variations induced by altitude in the chemical profile of bamboo species. The findings may possess fascinating active biological properties, thus offering an alternative use for bamboo.-
Descrição: dc.descriptionDepartment of Chemistry Faculty of Sciences Pontificia Universidad Javeriana-
Descrição: dc.descriptionInstitute of Chemistry São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Biology Faculty of Sciences Pontificia Universidad Javeriana-
Descrição: dc.descriptionFaculty of Agricultural Sciences Universidad Nacional de Colombia-
Descrição: dc.descriptionMetabolomics Core Facility-MetCore Universidad de los Andes-
Descrição: dc.descriptionDepartment of Botany and Zoology Universidad de Guadalajara-
Descrição: dc.descriptionInstitute of Chemistry São Paulo State University (UNESP)-
Idioma: dc.languageen-
Relação: dc.relationFrontiers in Molecular Biosciences-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectaltitudinal variation-
Palavras-chave: dc.subjectbamboo-
Palavras-chave: dc.subjectcinnamic acid derivatives-
Palavras-chave: dc.subjectflavonoids-
Palavras-chave: dc.subjectGNPS-
Palavras-chave: dc.subjectGuadua-
Palavras-chave: dc.subjectnatural products-
Palavras-chave: dc.subjectuntargeted metabolomics-
Título: dc.titleUntargeted metabolomics approach and molecular networking analysis reveal changes in chemical composition under the influence of altitudinal variation in bamboo species-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.