Physical Exercise Mitigates Salivary Gland and Saliva Damages in Rats Exposed to Binge-like Ethanol Pattern

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Federal do Pará (UFPA)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorState University of Pará-
Autor(es): dc.creatorPeinado, Beatriz Rodrigues Risuenho-
Autor(es): dc.creatorAragão, Walessa Alana Bragança-
Autor(es): dc.creatorPereira, Cristian dos Santos-
Autor(es): dc.creatorda Silva, Diane Cleydes Baia-
Autor(es): dc.creatorFerreira, Railson de Oliveira-
Autor(es): dc.creatorChaves-Neto, Antônio Hernandes-
Autor(es): dc.creatorFernandes, Luanna Melo Pereira-
Autor(es): dc.creatorLima, Rafael Rodrigues-
Data de aceite: dc.date.accessioned2025-08-21T21:07:59Z-
Data de disponibilização: dc.date.available2025-08-21T21:07:59Z-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-05-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3390/antiox12051038-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/247482-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/247482-
Descrição: dc.descriptionHeavy episodic ethanol (EtOH) consumption is a typical pattern, especially among younger people. The therapeutic effect of exercise on EtOH damage has not yet been fully elucidated. Therefore, this study aims to investigate whether moderate exercise can reduce the damage generated by ethanol consumption in salivary glands and saliva. Thus, 32 male Wistar rats were divided into four groups: control (sedentary animals treated with water); training (trained animals treated with EtOH); EtOH (sedentary animals treated with EtOH); and EtOH + training (trained animals treated with ethanol). EtOH was administered to the animals at a dose of 3 g/kg/day at a concentration of 20% w/v for three consecutive days per week via intragastric gavage. The training was performed on a treadmill for five successive days. At the end of the 4-week experimental protocol, the animals were euthanized, and salivary glands and saliva were collected for oxidative biochemistry analysis. Our results showed that EtOH consumption generated changes in the oxidative biochemistry of the salivary glands and saliva. Thus, it was possible to conclude that moderate physical exercise can significantly recover antioxidant activity, reducing the damage generated by EtOH.-
Descrição: dc.descriptionLaboratory of Functional and Structural Biology Institute of Biological Sciences Federal University of Pará-
Descrição: dc.descriptionDepartment of Basic Sciences School of Dentistry São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Morphology and Physiological Sciences Center of Sciences Biological and Health State University of Pará-
Descrição: dc.descriptionDepartment of Basic Sciences School of Dentistry São Paulo State University (UNESP)-
Idioma: dc.languageen-
Relação: dc.relationAntioxidants-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectalcohol-
Palavras-chave: dc.subjectbinge-drinking-
Palavras-chave: dc.subjectmoderate physical training-
Palavras-chave: dc.subjectoxidative biochemistry-
Palavras-chave: dc.subjectsalivary gland-
Título: dc.titlePhysical Exercise Mitigates Salivary Gland and Saliva Damages in Rats Exposed to Binge-like Ethanol Pattern-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.