Is maxillomandibular advancement an effective treatment for obstructive sleep apnea? Systematic literature review and meta-analysis

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.creatorTrindade, Paulo Alceu Kiemle-
Autor(es): dc.creatorNogueira, Vânia dos Santos Nunes-
Autor(es): dc.creatorWeber, Silke Anna Theresa-
Data de aceite: dc.date.accessioned2025-08-21T16:10:47Z-
Data de disponibilização: dc.date.available2025-08-21T16:10:47Z-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-05-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.bjorl.2023.02.007-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/247309-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/247309-
Descrição: dc.descriptionObjectives: To evaluate the effectiveness of maxillomandibular advancement surgery in the treatment of Obstructive Sleep Apnea by comparing the pre- and postoperative Apnea and Hypopnea Index, in addition to classifying the degree of evidence and risk of intervention bias. Methods: A systematic review of the literature was carried out in the PUBMED, LILACS, EMBASE, SCOPUS, WEB OF SCIENCE and COCHRANE platforms, including cohort studies with polysomnographic follow-up, without other associated pharyngeal or nasal surgical procedures. The risk of study bias was assessed using the Modified Delphi technique. Pre- and postoperative Apnea and Hypopnea Index data were plotted for meta-analysis, and the quality of evidence was assessed using the GRADE system. Results: Of 1882 references, 32 articles were selected for full-text reading, of which four studies were included, totaling 83 adults with obstructive sleep apnea who underwent maxillomandibular advancement. The meta-analysis was in favor of the intervention (DM = −33.36, 95% CI −41.43 to −25.29, p < 0.00001), with a mean percentage reduction in the Apnea and Hypopnea Index of 79.5% after surgery, even though the level of evidence was classified as very low quality by the GRADE system. Conclusion: The meta-analysis was in favor of the intervention, characterizing maxillomandibular advancement surgery as an effective treatment for obstructive sleep apnea in adults.-
Descrição: dc.descriptionUniversidade Estadual Paulista (UNESP) Faculdade de Medicina de Botucatu, SP-
Descrição: dc.descriptionUniversidade de São Paulo (USP) Hospital de Reabilitação de Anomalias Craniofaciais (HRAC), SP-
Descrição: dc.descriptionUniversidade Estadual Paulista (UNESP) Faculdade de Medicina de Botucatu, SP-
Formato: dc.format503-510-
Idioma: dc.languageen-
Relação: dc.relationBrazilian Journal of Otorhinolaryngology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectMaxillomandibular advancement-
Palavras-chave: dc.subjectOSA-
Palavras-chave: dc.subjectPolysomnography-
Título: dc.titleIs maxillomandibular advancement an effective treatment for obstructive sleep apnea? Systematic literature review and meta-analysis-
Tipo de arquivo: dc.typevídeo-
Aparece nas coleções:Repositório Institucional - Unesp

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