High-fat, high-sucrose, and combined high-fat/high-sucrose diets effects in oxidative stress and inflammation in male rats under presence or absence of obesity

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Autor(es): dc.contributorFederal University of Espírito Santo-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversity of Vila Velha-
Autor(es): dc.creatorKobi, Jéssika Butcovsky Botto Sarter-
Autor(es): dc.creatorMatias, Amanda Martins-
Autor(es): dc.creatorGasparini, Patrícia Vasconcelos Fontana-
Autor(es): dc.creatorTorezani-Sales, Suellem-
Autor(es): dc.creatorMadureira, Amanda Rangel-
Autor(es): dc.creatorda Silva, Daniel Sesana-
Autor(es): dc.creatorCorrea, Camila Renata-
Autor(es): dc.creatorGarcia, Jéssica Leite-
Autor(es): dc.creatorHaese, Douglas-
Autor(es): dc.creatorNogueira, Breno Valentim-
Autor(es): dc.creatorde Assis, Arícia Leone Evangelista Monteiro-
Autor(es): dc.creatorLima-Leopoldo, Ana Paula-
Autor(es): dc.creatorLeopoldo, André Soares-
Data de aceite: dc.date.accessioned2025-08-21T21:35:58Z-
Data de disponibilização: dc.date.available2025-08-21T21:35:58Z-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-04-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.14814/phy2.15635-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/247139-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/247139-
Descrição: dc.descriptionThe study examines the influence of three types of hypercaloric diets on metabolic parameters, inflammatory markers, and oxidative stress in experimental model. Male Wistar rats (n = 40) were randomized in control (C), high-sucrose (HS), high-fat (HF), and high-fat with sucrose (HFHS) for 20 weeks. Nutritional, metabolic, hormonal, and biochemical profiles, as well as histological analysis of adipose and hepatic tissues were performed. Inflammation and oxidative stress were determined. HF model caused obesity and comorbidities as glucose intolerance and arterial hypertension. In relation to hormonal and biochemical parameters, there was no significant difference between the groups. All groups showed increased deposition of fat droplets in the hepatic tissue, even though adipocyte areas were similar. Biomarkers of oxidative stress in serum and adipose tissues were similar among the groups. HF model was effective in triggering associated obesity and comorbidities in male rats, but all hypercaloric diets were unable to promote oxidative stress and inflammation.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa e Inovação do Espírito Santo-
Descrição: dc.descriptionPostgraduate Program in Nutrition and Health Health Sciences Center Federal University of Espírito Santo, Espírito Santo-
Descrição: dc.descriptionPostgraduate Program in Physiological Science Health Sciences Center Federal University of Espírito Santo, Espírito Santo-
Descrição: dc.descriptionPostgraduate Program in Physical Education Center of Physical Education and Sports Federal University of Espírito Santo, Espírito Santo-
Descrição: dc.descriptionThe Medical School São Paulo State University, São Paulo-
Descrição: dc.descriptionUniversity of Vila Velha, Espírito Santo-
Descrição: dc.descriptionDepartment of Morphology Health Sciences Center Federal University of Espírito Santo, Espírito Santo-
Descrição: dc.descriptionCenter of Physical Education and Sports Federal University of Espírito Santo, Espírito Santo-
Descrição: dc.descriptionThe Medical School São Paulo State University, São Paulo-
Descrição: dc.descriptionFundação de Amparo à Pesquisa e Inovação do Espírito Santo: 545/2018-
Idioma: dc.languageen-
Relação: dc.relationPhysiological Reports-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectdiets-
Palavras-chave: dc.subjectinflammation-
Palavras-chave: dc.subjectobesity-
Palavras-chave: dc.subjectoxidative stress-
Palavras-chave: dc.subjectrats-
Título: dc.titleHigh-fat, high-sucrose, and combined high-fat/high-sucrose diets effects in oxidative stress and inflammation in male rats under presence or absence of obesity-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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