Comparative study of the effect of different temperatures on bovine bone used for bone repair of critical calvaria defects in rats

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.creatorEgas, Lais Sara-
Autor(es): dc.creatorMatsumoto, Mariza Akemi-
Autor(es): dc.creatorHadad, Henrique-
Autor(es): dc.creatorTonini, Karen Rawen-
Autor(es): dc.creatorde Weert, Daniela Atili Brandini-
Autor(es): dc.creatorPerri de Carvalho, Paulo Sérgio-
Autor(es): dc.creatorPonzoni, Daniela-
Data de aceite: dc.date.accessioned2025-08-21T20:10:25Z-
Data de disponibilização: dc.date.available2025-08-21T20:10:25Z-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-05-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1002/jbm.b.35211-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/246486-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/246486-
Descrição: dc.descriptionTo evaluate the osteoconductive potential of inorganic biomaterials of bovine origin submitted to different temperatures in the bone repair of critical defects in rat calvaria. Forty-eight rats were divided into four groups according to the material used to fill the defect: control group (GC), the defect was filled only with blood clot (n = 12); GBO, defect filled with Bio-Oss®, deproteinzed at 300°C (n = 12); GOX, defect filled with Inorganic GenOx®, deproteinzed from 850 to 1200°C (n = 12) and G700, defect filled with Inorganic GenOx 700, deproteinzed at 700°C (n = 12). In each animal's calvaria, a trephine bur with 5 mm internal diameter was used to produce a 6 mm-diameter central defect. Gen Derm® resorbable bovine membrane was superimposed over all defects. Subsequently, animals were euthanized at 30 and 60 days after surgery. The pieces were sent for histological and histometric analysis to evaluate the following variables: bone neoformation, presence of biomaterial, mononuclear and polymorphonuclear leukocytes, presence of other tissues (granulation and medullary) and maturation of collagen fibers. The most representative group for bone neoformation was GC. At 30 days, there was a higher mean of mature bone tissue (75.8). At 60 days, there was no statistical difference between the GC (64.9), GBO (32.9), GOX (45.3), and G700 (26.6) groups. GBO presented the highest amount of biomaterial after 30 days (115.9) and 60 days (118.5). All bovine biomaterials were biocompatible and osteoconductive. GOX promoted the best bone repair of the studied materials.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery São Paulo State University (UNESP) Araçatuba School of Dentistry Brazil.-
Descrição: dc.descriptionDepartment of Basic Sciences State University (UNESP) School of Dentistry-
Descrição: dc.descriptionBauru School of Dentistry University of São Paulo – USP-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery São Paulo State University (UNESP) Araçatuba School of Dentistry Brazil.-
Descrição: dc.descriptionDepartment of Basic Sciences State University (UNESP) School of Dentistry-
Formato: dc.format1024-1034-
Idioma: dc.languageen-
Relação: dc.relationJournal of Biomedical Materials Research - Part B Applied Biomaterials-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectbiocompatible materials-
Palavras-chave: dc.subjectbone regeneration-
Palavras-chave: dc.subjectmodels animal-
Título: dc.titleComparative study of the effect of different temperatures on bovine bone used for bone repair of critical calvaria defects in rats-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.