Quantitative imaging of magnetic nanoparticles in an unshielded environment using a large AC susceptibility array

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorPhysikalisch-Technische Bundesanstalt-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade Federal de Goiás (UFG)-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.creatorSoares, Guilherme-
Autor(es): dc.creatorPinto, Leonardo-
Autor(es): dc.creatorLiebl, Maik-
Autor(es): dc.creatorBiasotti, Gabriel-
Autor(es): dc.creatorProspero, Andre-
Autor(es): dc.creatorStoppa, Erick-
Autor(es): dc.creatorBakuzis, Andris-
Autor(es): dc.creatorBaffa, Oswaldo-
Autor(es): dc.creatorWiekhorst, Frank-
Autor(es): dc.creatorMiranda, José Ricardo Arruda-
Data de aceite: dc.date.accessioned2025-08-21T15:59:13Z-
Data de disponibilização: dc.date.available2025-08-21T15:59:13Z-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2022-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1186/s13036-022-00305-9-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/246056-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/246056-
Descrição: dc.descriptionBackground: Non-invasive magnetic imaging techniques are necessary to assist magnetic nanoparticles in biomedical applications, mainly detecting their distribution inside the body. In Alternating Current Biosusceptometry (ACB), the magnetic nanoparticle's magnetization response under an oscillating magnetic field, which is applied through an excitation coil, is detected with a balanced detection coil system. Results: We built a Multi-Channel ACB system (MC-ACB) containing nineteen pick-up coils and obtained 2D quantitative images of magnetic nanoparticle distributions by solving an inverse problem. We reconstructed the magnetic nanoparticles spatial distributions in a field of view of 14 × 14 cm2 with a spatial resolution of 2.0 cm and sensitivity in the milligram scale. A correlation coefficient between quantitative reconstructed and nominal magnetic nanoparticle distributions above 0.6 was found for all measurements. Conclusion: Besides other interesting features such as sufficient large field of view dimension for mice and rat studies, portability, and the ability to assess the quantitative magnetic nanoparticles distributions in real-time, the MC-ACB system is a promising tool for quantitative imaging of magnetic nanoparticles distributions in real-time, offering an affordable setup for easy access in clinical or laboratory environments.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionPhysikalisch-Technische Bundesanstalt, Abbestraße 2–12-
Descrição: dc.descriptionBiosciences Institute of Botucatu São Paulo State University, Botucatu-
Descrição: dc.descriptionInstitute of Physics Federal University of Goiás-
Descrição: dc.descriptionFaculty of Philosophy Sciences and Letters at Ribeirão Preto University of São Paulo, Ribeirão Preto, Sao Paulo-
Descrição: dc.descriptionBiosciences Institute of Botucatu São Paulo State University, Botucatu-
Descrição: dc.descriptionFAPESP: 2021/09829-4-
Descrição: dc.descriptionCNPq: 311074/2018-9-
Idioma: dc.languageen-
Relação: dc.relationJournal of Biological Engineering-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAlternate current biosusceptometry-
Palavras-chave: dc.subjectInverse problem-
Palavras-chave: dc.subjectMagnetic nanoparticles-
Palavras-chave: dc.subjectQuantitative imaging-
Título: dc.titleQuantitative imaging of magnetic nanoparticles in an unshielded environment using a large AC susceptibility array-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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