Process strategies to reduce cellulase enzyme loading for renewable sugar production in biorefineries

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorEARTH University-
Autor(es): dc.contributorUniversidade Federal de Santa Catarina (UFSC)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorFederal University of Alfenas-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorFederal University of Paraná-
Autor(es): dc.contributorKLE Technological University-
Autor(es): dc.contributorUPES-
Autor(es): dc.creatorReis, Cristiano E. Rodrigues-
Autor(es): dc.creatorLibardi Junior, Nelson-
Autor(es): dc.creatorBento, Heitor B.S.-
Autor(es): dc.creatorCarvalho, Ana Karine F. de-
Autor(es): dc.creatorVandenberghe, Luciana Porto de Souza-
Autor(es): dc.creatorSoccol, Carlos Ricardo-
Autor(es): dc.creatorAminabhavi, Tejraj M.-
Autor(es): dc.creatorChandel, Anuj K.-
Data de aceite: dc.date.accessioned2025-08-21T16:19:38Z-
Data de disponibilização: dc.date.available2025-08-21T16:19:38Z-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2022-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.cej.2022.138690-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/245890-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/245890-
Descrição: dc.descriptionSecond-generation (2G) sugar is the principal building block in biorefineries producing sustainable fuels, green chemicals, and materials. Its production involves a pre-treatment strategy, which can remove either hemicellulose or lignin, followed by a cellulase cocktail-mediated hydrolysis of pre-treated biomass applying numerous modifications. The high production cost of sugar from biomass using high-solid loadings with the desired purity is the important limiting factor for their economic conversion into bio-renewables. Pre-treatment and cellulase-mediated enzymatic hydrolysis of recalcitrant biomass are among the major technical and economic impediments to the overall success of biorefineries. Critical parameters such as the high amount of cellulase required for biomass hydrolysis, high cellulase cost, unproductive binding of cellulase to lignin, inhibitive reactions, and lower substrate applicability directly influence the recovery of sugar at a competitive price. Understanding the interaction of the relationship of the enzymes and substrates with the interactions of the reducing cellulase amount and effective hydrolysis rate should be positioned for the recovery of 2G sugar at a competitive price. Thus, effective strategies are needed to minimize cellulase dosage to overcome the cost of the enzyme. Further, on-site enzyme production, the addition of pre-treated biomass in fed-batch mode, and the washing of pre-treated biomass can play a pivotal role in the economic production of 2G sugar. This review provides a comprehensive analysis of the specific strategies such as applying extraneous proteins and additives, enzyme recycling, and effect of washing pre-treated biomass on 2G sugar production at a large scales in lignocellulose biorefineries.-
Descrição: dc.descriptionEARTH University, Las Mercedes, Guácimo-
Descrição: dc.descriptionSanitary and Environmental Engineering Department Federal University of Santa Catarina, Santa Catarina-
Descrição: dc.descriptionDepartment of Bioprocess Engineering and Biotechnology School of Pharmaceutical Sciences São Paulo State University, Araraquara-
Descrição: dc.descriptionPostgraduate Program in Biotechnology Institute of Chemistry Federal University of Alfenas, Minas Gerais-
Descrição: dc.descriptionEngineering School of Lorena University of São Paulo, Lorena-
Descrição: dc.descriptionBioprocess Engineering and Biotechnology Department Federal University of Paraná, Paraná-
Descrição: dc.descriptionSchool of Advanced Sciences KLE Technological University-
Descrição: dc.descriptionSchool of Engineering UPES, Bidholi, Uttarakhand-
Descrição: dc.descriptionDepartment of Bioprocess Engineering and Biotechnology School of Pharmaceutical Sciences São Paulo State University, Araraquara-
Idioma: dc.languageen-
Relação: dc.relationChemical Engineering Journal-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBiomass hydrolysis-
Palavras-chave: dc.subjectBiorefinery-
Palavras-chave: dc.subjectCellulase-
Palavras-chave: dc.subjectPre-treatment-
Palavras-chave: dc.subjectSecond-generation sugar-
Título: dc.titleProcess strategies to reduce cellulase enzyme loading for renewable sugar production in biorefineries-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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