Hepatic epithelioid hemangioendothelioma: how fast does it grow and which findings could have prevented diagnostic delay?-a case report

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorHosp Estadual Bauru-
Autor(es): dc.contributorClin Hosp-
Autor(es): dc.contributorGen Hosp Shenyang Mil Area-
Autor(es): dc.creatorRibeiro, Michele Costa de Oliveira-
Autor(es): dc.creatorLemos, Juliana Viana Baiao-
Autor(es): dc.creatorMoraes, Marcelo Padovani de Toledo-
Autor(es): dc.creatorOliver, Felipe Aguera-
Autor(es): dc.creatorAlvarez, Matheus-
Autor(es): dc.creatorSilva, Giovanni Faria-
Autor(es): dc.creatorQi, Xingshun-
Autor(es): dc.creatorRomeiro, Fernando Gomes-
Data de aceite: dc.date.accessioned2025-08-21T17:41:49Z-
Data de disponibilização: dc.date.available2025-08-21T17:41:49Z-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2022-07-29-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.21037/tgh-22-48-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/245482-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/245482-
Descrição: dc.descriptionBackground: Hepatic epithelioid hemangioendothelioma (HEHE) is a rare neoplastic disease of varied presentation and unspecific radiological signs in the early stages. The diagnostic delay can lead to metastatic disease, thus increasing the tumor burden and reducing the treatment options. HEHE is usually deemed a slow-growing tumor, but its speed of growth is poorly reported and still unknown.Case Description: In this case report, we documented a HEHE diagnosed in a young woman who had complaints of abdominal pain, weight loss and bloating for a long time. The typical findings observed in histological studies were not promptly recognized in the histological analyzes, even after two laparoscopicguided liver biopsies, delaying the diagnosis until extrahepatic tumor spreading. Findings observed in computed tomography, magnetic resonance imaging and histological studies are presented. The coalescence of nodules and the rising of giant masses, occupying large parts of the liver in a specific time span, were registered and quantified. As opposed to prior reports, the results show that hepatic HEHE can grow rapidly, reinforcing the need of early diagnosis, thus avoiding the complications presented herein.Conclusions: The findings observed via radiological and histological imaging that could have avoided the diagnosis delay are depicted and discussed, showing that HEHE can rise faster than previously documented.-
Descrição: dc.descriptionFunda��o de Amparo � Pesquisa do Estado de S�o Paulo (FAPESP)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Cient�fico e Tecnol�gico (CNPq)-
Descrição: dc.descriptionUniv Estadual Paulista Julio Mesquita Filho UNESP, Botucatu Sch Med, Dept Internal Med, Gastroenterol Div, Botucatu, Brazil-
Descrição: dc.descriptionHosp Estadual Bauru, Fundacao Desenvolvimento Med & Hosp FAMESP, Bauru, Brazil-
Descrição: dc.descriptionUniv Estadual Paulista Julio Mesquita Filho UNESP, Botucatu Sch Med, Dept Pathol, Botucatu, Brazil-
Descrição: dc.descriptionUniv Estadual Paulista Julio Mesquita Filho UNESP, Botucatu Sch Med, Dept Radiol, Botucatu, Brazil-
Descrição: dc.descriptionClin Hosp, Ctr Med Phys & Radiat Protect, FMB HC, Botucatu Sch Med, Botucatu, Brazil-
Descrição: dc.descriptionGen Hosp Shenyang Mil Area, Gen Hosp Northern Theater Command, Dept Gastroenterol, Shenyang, Peoples R China-
Descrição: dc.descriptionSao Paulo State Univ UNSEP, Botucatu Sch Med, Dept Internal Med, Gastroenterol Div, Dist Rubiao Jr S N, BR-18608917 Sao Paulo, Brazil-
Descrição: dc.descriptionUniv Estadual Paulista Julio Mesquita Filho UNESP, Botucatu Sch Med, Dept Internal Med, Gastroenterol Div, Botucatu, Brazil-
Descrição: dc.descriptionUniv Estadual Paulista Julio Mesquita Filho UNESP, Botucatu Sch Med, Dept Pathol, Botucatu, Brazil-
Descrição: dc.descriptionUniv Estadual Paulista Julio Mesquita Filho UNESP, Botucatu Sch Med, Dept Radiol, Botucatu, Brazil-
Descrição: dc.descriptionSao Paulo State Univ UNSEP, Botucatu Sch Med, Dept Internal Med, Gastroenterol Div, Dist Rubiao Jr S N, BR-18608917 Sao Paulo, Brazil-
Descrição: dc.descriptionFAPESP: 2017/25592-9)-
Formato: dc.format9-
Idioma: dc.languageen-
Publicador: dc.publisherAme Publishing Company-
Relação: dc.relationTranslational Gastroenterology And Hepatology-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectLiver cancer-
Palavras-chave: dc.subjectextrahepatic metastasis-
Palavras-chave: dc.subjectimaging-
Palavras-chave: dc.subjectliver neoplasms-
Palavras-chave: dc.subjectcase report-
Título: dc.titleHepatic epithelioid hemangioendothelioma: how fast does it grow and which findings could have prevented diagnostic delay?-a case report-
Tipo de arquivo: dc.typelivro digital-
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