Effects of 48-hour feed deprivation on acute-phase response in horses

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual do Norte Fluminense Darcy Ribeiro (UENF)-
Autor(es): dc.contributorUniversidade Federal de Viçosa (UFV)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorFilippo, Paula Alessandra Di-
Autor(es): dc.creatorDuarte, Bárbara Ribeiro-
Autor(es): dc.creatorAlbernaz, Antônio Peixoto-
Autor(es): dc.creatorFonseca, Leandro Abreu Da-
Autor(es): dc.creatorViana, Inácio Silva-
Autor(es): dc.creatorQuirino, Célia Raquel-
Data de aceite: dc.date.accessioned2025-08-21T23:31:48Z-
Data de disponibilização: dc.date.available2025-08-21T23:31:48Z-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2023-07-29-
Data de envio: dc.date.issued2022-09-09-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1590/1809-6891v23e-72445E-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/244859-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/244859-
Descrição: dc.descriptionThe objective of this study was to evaluate the effect of feed restriction on acute-phase response in horses. Twenty horses were deprived of food for 48 h and others 12 animals (control) had free access to water and hay. They were closely monitored and examined, and blood samples were taken at the beginning (0) of the study and 6, 12, 18, 24, 30, 36, 42 and 48 hours afterward. Data were submitted to two-way analysis of variance with repeated measures and statistical significance was P ≤ 0.05. The horses tolerated feed restriction without serious clinical complications. Feed restriction induced an increase in the acute-phase response by elevating serum concentrations of α2-macroglobulin (24-38 h), ceruloplasmin (36-48 h), α1-antitrypsin (30-48 h), α1-acid glycoprotein (42-48 h) and haptoglobin (42-48 h). Nutrient deprivation raised the levels of circulating cortisol, which acts on the innate immune system, which then induces the acute-phase response. In conclusion, food restriction is a physical stressor for horses, capable of inducing an acute-phase protein reaction, characterized by increased production of α2-macroglobulin, ceruloplasmin, α1- antitrypsin, α1-acid glycoprotein and haptoglobin.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionUniversidade Estadual do Norte Fluminense Darcy Ribeiro (UENF)-
Descrição: dc.descriptionUniversidade Federal de Viçosa (UFV)-
Descrição: dc.descriptionUniversidade Estadual Paulista Júlio de Mesquita Filho (UNESP)-
Descrição: dc.descriptionUniversidade Estadual Paulista Júlio de Mesquita Filho (UNESP)-
Descrição: dc.descriptionCAPES: 001-
Formato: dc.format--
Formato: dc.formatapplication/pdf-
Idioma: dc.languageen-
Publicador: dc.publisherUniversidade Federal de Goiás-
Relação: dc.relationCiência Animal Brasileira-
Direitos: dc.rightsinfo:eu-repo/semantics/openAccess-
???dc.source???: dc.sourceSciELO-
Palavras-chave: dc.subjectEquine-
Palavras-chave: dc.subjectFeed restriction-
Palavras-chave: dc.subjectInflammation-
Palavras-chave: dc.subjectImmune response-
Palavras-chave: dc.subjectProteins-
Palavras-chave: dc.subjectStress-
Título: dc.titleEffects of 48-hour feed deprivation on acute-phase response in horses-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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