Effects of Sodium Hexametaphosphate and Fluoride on the pH and Inorganic Components of Streptococcus mutans and Candida albicans Biofilm after Sucrose Exposure

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversity of Western São Paulo (UNOESTE)-
Autor(es): dc.creatorHosida, Thayse Yumi-
Autor(es): dc.creatorPessan, Juliano Pelim-
Autor(es): dc.creatorCavazana, Thamires Priscila-
Autor(es): dc.creatorSampaio, Caio-
Autor(es): dc.creatorde Morais, Leonardo Antônio-
Autor(es): dc.creatorMonteiro, Douglas Roberto-
Autor(es): dc.creatorDelbem, Alberto Carlos Botazzo-
Data de aceite: dc.date.accessioned2025-08-21T22:06:09Z-
Data de disponibilização: dc.date.available2025-08-21T22:06:09Z-
Data de envio: dc.date.issued2023-03-02-
Data de envio: dc.date.issued2023-03-02-
Data de envio: dc.date.issued2022-08-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3390/antibiotics11081044-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/242250-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/242250-
Descrição: dc.descriptionIn order to improve the anticaries effects of fluoridated products, the supplementation of these products has been considered a promising alternative for caries control. This study evaluated the effects of sodium hexametaphosphate (HMP) and/or fluoride (F) on the inorganic components and pH of Streptococcus mutans and Candida albicans dual-species biofilms. The biofilms were treated 72, 78, and 96 h after the beginning of their formation with 0.25, 0.5, or 1% HMP-containing solutions with or without F (500 ppm, as sodium fluoride). F-containing solutions (500 ppm and 1100 ppm) and artificial saliva were used as controls. The biofilms were exposed to a 20% sucrose solution after the third treatment. Along with the biofilm pH, the concentrations of F, calcium, phosphorus (P), and HMP were determined. HMP, combined with F, increased F levels and decreased P levels in the biofilm fluid compared to that of the solution with 500 ppm F. Exposure to sucrose decreased the concentrations of all ions in the biomass, except for HMP; 1% HMP, combined with F, promoted the highest pH. It can be concluded that HMP affected the inorganic composition of the biofilm and exerted a buffering effect on the biofilm pH.-
Descrição: dc.descriptionDepartment of Preventive and Restorative Dentistry School of Dentistry São Paulo State University (UNESP), São Paulo-
Descrição: dc.descriptionPostgraduate Program in Health Sciences University of Western São Paulo (UNOESTE), São Paulo-
Descrição: dc.descriptionDepartment of Preventive and Restorative Dentistry School of Dentistry São Paulo State University (UNESP), São Paulo-
Idioma: dc.languageen-
Relação: dc.relationAntibiotics-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectbiofilms-
Palavras-chave: dc.subjectCandida albicans-
Palavras-chave: dc.subjectfluorides-
Palavras-chave: dc.subjecthexametaphosphate-
Palavras-chave: dc.subjectHMP-
Palavras-chave: dc.subjectphosphates-
Palavras-chave: dc.subjectStreptococcus mutans-
Título: dc.titleEffects of Sodium Hexametaphosphate and Fluoride on the pH and Inorganic Components of Streptococcus mutans and Candida albicans Biofilm after Sucrose Exposure-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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