Biological and chemical properties of five mineral oxides and of mineral trioxide aggregate repair high plasticity: an in vitro study

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorAeronautics Technological Institute (ITA)-
Autor(es): dc.contributorSyrian Private University (S.P.U)-
Autor(es): dc.creatorAbu Hasna, Amjad-
Autor(es): dc.creatorde Paula Ramos, Lucas-
Autor(es): dc.creatorCampos, Tiago Moreira Bastos-
Autor(es): dc.creatorde Castro Lopes, Sergio Lucio Pereira-
Autor(es): dc.creatorRachi, Maisour Ala-
Autor(es): dc.creatorde Oliveira, Luciane Dias-
Autor(es): dc.creatorCarvalho, Cláudio Antonio Talge-
Data de aceite: dc.date.accessioned2025-08-21T22:13:28Z-
Data de disponibilização: dc.date.available2025-08-21T22:13:28Z-
Data de envio: dc.date.issued2023-03-02-
Data de envio: dc.date.issued2023-03-02-
Data de envio: dc.date.issued2022-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1038/s41598-022-17854-0-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/242218-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/242218-
Descrição: dc.descriptionCalcium silicate-based cements have diverse applications in endodontics. This study aimed to evaluate the antibiofilm action, biocompatibility, morphological structure, chemical composition and radiopacity of Five Mineral Oxides (5MO), Mineral Trioxide Aggregate Repair High Plasticity (MTA Repair HP), and Mineral Trioxide Aggregate (MTA) cements. MTT analysis was used to test the antibiofilm action of these cements against five anaerobic microorganisms, and test their biocompatibility with mouse macrophage (RAW 264.7) and osteoblasts (MG-63) cultures. Their morphological structure and chemical composition were evaluated by scanning electron microscopy (SEM) coupled to energy dispersion X-ray spectroscopy (EDX), and the phase analysis was performed by X-ray diffraction (XRD). Conventional radiography was used to assess the radiopacity of the cements. 5MO, MTA Repair HP and MTA were effective against Porphyromonas gingivalis, Parvimonas micra, Fusobacterium nucleatum and Prevotella intermedia, they were biocompatible with macrophages and osteoblasts after 5 min of contact, and they had adequate radiopacity to be used clinically. Bismuth oxide (Bi2O3) is used as a radiopacifier in MTA and 5MO, and calcium tungstate, in MTA Repair HP. Titanium dioxide (TiO2) (ANATASE) is responsible for the antimicrobial action and biocompatibility of 5MO.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionDepartment of Restorative Dentistry Endodontics Division Institute of Science and Technology São Paulo State University – UNESP, Av. Eng. Francisco José Longo Avenue 777, São Paulo-
Descrição: dc.descriptionDepartment of Biosciences and Oral Diagnosis Institute of Science and Technology São Paulo State University – UNESP, São Paulo-
Descrição: dc.descriptionPhysics Department Aeronautics Technological Institute (ITA), São Paulo-
Descrição: dc.descriptionDepartment of Operative Dentistry Syrian Private University (S.P.U)-
Descrição: dc.descriptionDepartment of Restorative Dentistry Endodontics Division Institute of Science and Technology São Paulo State University – UNESP, Av. Eng. Francisco José Longo Avenue 777, São Paulo-
Descrição: dc.descriptionDepartment of Biosciences and Oral Diagnosis Institute of Science and Technology São Paulo State University – UNESP, São Paulo-
Descrição: dc.descriptionCAPES: 2018/13930-0-
Idioma: dc.languageen-
Relação: dc.relationScientific Reports-
???dc.source???: dc.sourceScopus-
Título: dc.titleBiological and chemical properties of five mineral oxides and of mineral trioxide aggregate repair high plasticity: an in vitro study-
Tipo de arquivo: dc.typelivro digital-
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