Antiglycation, antioxidant and cytotoxicity activities of crude extract of Turnera ulmifolia L. before and after microencapsulation process

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorFundação Educacional do Município de Assis (FEMA)-
Autor(es): dc.contributorUniversidade Federal do Rio de Janeiro (UFRJ)-
Autor(es): dc.creatorViel, Amanda Martins-
Autor(es): dc.creatorFigueiredo, Célia Cristina Malaguti-
Autor(es): dc.creatorGranero, Filipe Oliveira-
Autor(es): dc.creatorSilva, Luciana Pereira-
Autor(es): dc.creatorXimenes, Valdecir Farias-
Autor(es): dc.creatorGodoy, Thais Miranda-
Autor(es): dc.creatorQuintas, Luis Eduardo Menezes-
Autor(es): dc.creatorSilva, Regildo Márcio Gonçalves da-
Data de aceite: dc.date.accessioned2025-08-21T18:22:31Z-
Data de disponibilização: dc.date.available2025-08-21T18:22:31Z-
Data de envio: dc.date.issued2023-03-02-
Data de envio: dc.date.issued2023-03-02-
Data de envio: dc.date.issued2022-09-20-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.jpba.2022.114975-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/242182-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/242182-
Descrição: dc.descriptionTurnera ulmifolia L. is used in folk medicine and it is known to have anti-hyperglycemic effect on the organism in order to reduce complications in diabetic patients. Glycation process is directly related to oxidative stress, acting as an important endogenous source, inducing the production of free radicals, and thus increasing the production of reactive oxygen species. The encapsulation technology on natural compounds can minimize and even mitigate the risk of loss of biological activity in order to maintain their activities against oxidative stress and glycation. The present study aimed to evaluate the antiglycation and antioxidant activities of T. ulmifolia extract before and after encapsulation and cytotoxicity of the crude extract. This study presents important information about the biological activities, highlighting antioxidant and antiglycation potential and no cytotoxicity of Turnera ulmifolia crude extract, a species of genus Turnera that has been poorly studied. T. ulmifolia crude extract presented flavonoids as main active compounds. The results showed a promising activity in scavenging free and peroxyl radicals, chelating iron ions and inhibiting BSA glycation. In addition, this study showed the possible encapsulation of bioactive compounds using maltodextrin as wall material.-
Descrição: dc.descriptionSão Paulo State University (UNESP) Institute of Chemistry, São Paulo-
Descrição: dc.descriptionFundação Educacional do Município de Assis (FEMA), São Paulo-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Sciences Department of Chemistry-
Descrição: dc.descriptionFederal University of Rio de Janeiro (UFRJ) Institute of Biomedical Sciences Laboratory of Biochemical and Molecular Pharmacology, Rio de Janeiro-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Sciences Humanities and Languages Department of Biotechnology Laboratory of Phytotherapic and Natural Products, São Paulo-
Descrição: dc.descriptionSão Paulo State University (UNESP) Institute of Chemistry, São Paulo-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Sciences Department of Chemistry-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Sciences Humanities and Languages Department of Biotechnology Laboratory of Phytotherapic and Natural Products, São Paulo-
Idioma: dc.languageen-
Relação: dc.relationJournal of Pharmaceutical and Biomedical Analysis-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectFlavonoids-
Palavras-chave: dc.subjectMicrocapsules-
Palavras-chave: dc.subjectOxidative stress-
Palavras-chave: dc.subjectProtein glycation-
Palavras-chave: dc.subjectTurnera ulmifolia L-
Título: dc.titleAntiglycation, antioxidant and cytotoxicity activities of crude extract of Turnera ulmifolia L. before and after microencapsulation process-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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