Polycaprolactone/chlorinated bioglass scaffolds doped with Mg and Li ions: Morphological, physicochemical, and biological analysis

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorTechnological Institute of Aeronautics (ITA)-
Autor(es): dc.creatorKukulka, Elisa Camargo-
Autor(es): dc.creatorde Souza, Joyce Rodrigues-
Autor(es): dc.creatorde Araújo, Juliani Carolini Ribeiro-
Autor(es): dc.creatorde Vasconcellos, Luana Marotta Reis-
Autor(es): dc.creatorCampos, Tiago Moreira Bastos-
Autor(es): dc.creatorThim, Gilmar Patricínio-
Autor(es): dc.creatorBorges, Alexandre Luiz Souto-
Data de aceite: dc.date.accessioned2025-08-21T22:55:41Z-
Data de disponibilização: dc.date.available2025-08-21T22:55:41Z-
Data de envio: dc.date.issued2023-03-02-
Data de envio: dc.date.issued2023-03-02-
Data de envio: dc.date.issued2021-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1002/jbm.b.35140-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/242042-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/242042-
Descrição: dc.descriptionThe objective was to synthesize and characterize fine polycaprolactone (PCL) fibers associated with a new 58S bioglass obtained by the precipitated sol–gel route, produced by the electrospinning process in order to incorporate therapeutic ions (Mg and Li). In PCL/acetone solutions were added 7% pure bioglass, bioglass doped with Mg(NO3)2 and Li2CO3 and were subjected to electrospinning process. The fibers obtained were characterized morphologically, chemically and biologically. The results showed the presence of fine fibers at the nanometric scale and with diameters ranging from 0.67 to 1.92 μm among groups. Groups containing bioglass showed particles both inside and on the surface of the fibers. The components of the polymer, bioglass and therapeutic ions were present in the fibers produced. The produced fibers showed cell viability and induced the formation of mineralization nodules. It was observed the applicability of that methodology in making an improved biomaterial, which adds the osteoinductive properties of the bioglass to PCL and to those of therapeutic ions, applicable to guided bone regeneration.-
Descrição: dc.descriptionDepartment of Dental Materials and Prosthesis Institute of Science and Technology São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Bioscience and Oral Diagnosis Institute of Science and Technology São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Physics Technological Institute of Aeronautics (ITA)-
Descrição: dc.descriptionDepartment of Dental Materials and Prosthesis Institute of Science and Technology São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Bioscience and Oral Diagnosis Institute of Science and Technology São Paulo State University (UNESP)-
Idioma: dc.languageen-
Relação: dc.relationJournal of Biomedical Materials Research - Part B Applied Biomaterials-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectbiocompatible materials-
Palavras-chave: dc.subjectbioglass-
Palavras-chave: dc.subjectbone regeneration-
Palavras-chave: dc.subjectregenerative medicine-
Palavras-chave: dc.subjecttissue scaffolds-
Título: dc.titlePolycaprolactone/chlorinated bioglass scaffolds doped with Mg and Li ions: Morphological, physicochemical, and biological analysis-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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