Innovative strategy for in-office tooth bleaching using violet LED and biopolymers as H2O2 catalysts

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorMartins, Beatriz Voss-
Autor(es): dc.creatorDias, Marlon Ferreira-
Autor(es): dc.creatorde Oliveira Ribeiro, Rafael Antônio-
Autor(es): dc.creatorLeite, Maria Luísa de Alencar e Silva-
Autor(es): dc.creatorHebling, Josimeri-
Autor(es): dc.creatorde Souza Costa, Carlos Alberto-
Data de aceite: dc.date.accessioned2025-08-21T16:27:13Z-
Data de disponibilização: dc.date.available2025-08-21T16:27:13Z-
Data de envio: dc.date.issued2023-03-02-
Data de envio: dc.date.issued2023-03-02-
Data de envio: dc.date.issued2022-06-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.pdpdt.2022.102886-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/241813-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/241813-
Descrição: dc.descriptionObjective: To assess the influence of coating the enamel with a nanofiber scaffold (NS) and a polymeric catalyst primer (PCP) on the esthetic efficacy, degradation kinetics of hydrogen peroxide (H2O2), and trans-amelodentinal cytotoxicity of bleaching gels subjected or not to violet-LED irradiation. Methodology: The following groups were established (n = 8): G1- No treatment (negative control); G2- NS+PCP; G3- LED; G4- NS+PCP+LED; G5- 35% H2O2 (positive control); G6- NS+PCP+35% H2O2+LED; G7- 20% H2O2; G8- NS+PCP+20% H2O2+LED; G9- 10% H2O2; G10- NS+PCP+10% H2O2+LED. For esthetic efficacy analysis, enamel/dentin discs were stained and exposed for 45 min to the bleaching protocols. To assess the cytotoxicity, the stained enamel/dentin discs were adapted to artificial pulp chambers, and the extracts (culture medium + components diffused through the discs) were collected and applied to MDPC-23 cells, which had their viability, oxidative stress, and morphology (SEM) evaluated. The amount of H2O2 diffused and hydroxyl radical (OH•) production were also determined (two-way ANOVA/Tukey/paired Student t-test; p < 0.05). Results: G6 had the highest esthetic efficacy compared to the other groups (p < 0.05). Besides the esthetic efficacy similar to conventional in-office bleaching (G5; p > 0.05), G10 also showed the lowest toxic effect and oxidative stress to MDPC-23 cells compared to all bleached groups (p < 0.05). Conclusion: Coating the enamel with a nanofiber scaffold and a polymeric catalyst primer, followed by the application of 10%, 20%, or 35% H2O2 bleaching gels irradiated with a violet LED, stimulates H2O2 degradation, increasing esthetic efficacy and reducing the trans-amelodentinal toxicity of the treatment.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionDepartment of Dental Materials and Prosthodontics São Paulo State University (UNESP) School of Dentistry-
Descrição: dc.descriptionDepartment of Morphology Genetics Orthodontics and Pediatric Dentistry São Paulo State University (UNESP) School of Dentistry-
Descrição: dc.descriptionDepartment of Physiology and Pathology São Paulo State University (UNESP) School of Dentistry-
Descrição: dc.descriptionDepartment of Dental Materials and Prosthodontics São Paulo State University (UNESP) School of Dentistry-
Descrição: dc.descriptionDepartment of Morphology Genetics Orthodontics and Pediatric Dentistry São Paulo State University (UNESP) School of Dentistry-
Descrição: dc.descriptionDepartment of Physiology and Pathology São Paulo State University (UNESP) School of Dentistry-
Descrição: dc.descriptionCAPES: 001-
Descrição: dc.descriptionFAPESP: 2020/08882–6-
Idioma: dc.languageen-
Relação: dc.relationPhotodiagnosis and Photodynamic Therapy-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCytotoxicity-
Palavras-chave: dc.subjectOdontoblasts-
Palavras-chave: dc.subjectTooth bleaching-
Palavras-chave: dc.subjectviolet-
Título: dc.titleInnovative strategy for in-office tooth bleaching using violet LED and biopolymers as H2O2 catalysts-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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