Development of a sodium fluoride and stannous chloride-containing gel for treatment of dental erosion

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorPereira, Laís Gatti de Souza-
Autor(es): dc.creatorBezerra, Sávio José Cardoso-
Autor(es): dc.creatorViana, Ítallo Emídio Lira-
Autor(es): dc.creatorde Lima, Leonardo Custódio-
Autor(es): dc.creatorBorges, Alessandra Bühler-
Autor(es): dc.creatorScaramucci, Taís-
Data de aceite: dc.date.accessioned2025-08-21T16:59:22Z-
Data de disponibilização: dc.date.available2025-08-21T16:59:22Z-
Data de envio: dc.date.issued2023-03-01-
Data de envio: dc.date.issued2023-03-01-
Data de envio: dc.date.issued2021-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1590/0103-6440202204808-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/241537-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/241537-
Descrição: dc.descriptionThis study synthesized and tested experimental gels containing fluoride (F-) and stannous (Sn2+) ions for the control of dental erosion. Enamel and dentin polished specimens were eroded (1% citric acid solution, 10 min) and randomly allocated into 5 groups (n=10): Placebo-Hydroxypropyl Methylcellulose (HMC) gel; F+Sn+HMC-7,500 ppm F- / 15,000 ppm Sn2+; F+HMC-7,500 ppm F-; Commercial acidulated phosphate fluoride gel (12,300 ppm F-); and Control-no treatment. After treatment (applied for 60 s), specimens underwent an erosion-remineralization cycling (5 min in 0.3% citric acid solution, 60 min in artificial saliva, 4×/day, 20 days). Surface loss (SL, in µm) was determined after the 5th, 10th and 20th days of cycling (α=0.05). For enamel, after 5 and 10 days, F+Sn+HMC presented the lowest SL, which did not differ from the commercial gel. After 20 days, no differences were found between commercial, F+HMC, and F+Sn+HMC groups. Placebo did not differ from the control at any time points, and both groups presented the highest SL when compared to the other groups. For dentin, on the 5th day, F+Sn+HMC, F+HMC and commercial did not differ significantly, showing lower SL than the control and the placebo. On the 10th day, F+Sn+HMC and commercial presented the lowest SL compared to control and placebo. After 20 days, only the commercial gel showed lower SL than the control and placebo. Thus, the experimental F+Sn+HMC gel was able to control the progression of tooth erosion.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionDepartment of Restorative Dentistry University of São Paulo School of Dentistry, Av. Prof. Lineu Prestes 2227, SP-
Descrição: dc.descriptionDepartment of Restorative Dentistry at Institute of Science and Technology of São José dos Campos UNESP São Paulo State University, Av. Engenheiro Francisco José Longo 777, SP-
Descrição: dc.descriptionDepartment of Restorative Dentistry at Institute of Science and Technology of São José dos Campos UNESP São Paulo State University, Av. Engenheiro Francisco José Longo 777, SP-
Descrição: dc.descriptionFAPESP: 2020/07986-2-
Formato: dc.format54-61-
Idioma: dc.languageen-
Relação: dc.relationBrazilian Dental Journal-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectdental erosion-
Palavras-chave: dc.subjecterosive tooth wear-
Palavras-chave: dc.subjectfluoride-
Palavras-chave: dc.subjectgel-
Palavras-chave: dc.subjectstannous-
Título: dc.titleDevelopment of a sodium fluoride and stannous chloride-containing gel for treatment of dental erosion-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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