Pharmaceutical nanotechnology: Antimicrobial peptides as potential new drugs against WHO list of critical, high, and medium priority bacteria

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorFacultad de Ciencias Farmacéuticas Bioquímicas y Biotecnológicas-
Autor(es): dc.contributorUniversity of Brasilia-
Autor(es): dc.creatorRoque-Borda, Cesar Augusto-
Autor(es): dc.creatorBento da Silva, Patricia-
Autor(es): dc.creatorRodrigues, Mosar Corrêa-
Autor(es): dc.creatorDi Filippo, Leonardo Delello-
Autor(es): dc.creatorDuarte, Jonatas L.-
Autor(es): dc.creatorChorilli, Marlus-
Autor(es): dc.creatorVicente, Eduardo Festozo-
Autor(es): dc.creatorGarrido, Saulo Santesso-
Autor(es): dc.creatorRogério Pavan, Fernando-
Data de aceite: dc.date.accessioned2025-08-21T15:26:29Z-
Data de disponibilização: dc.date.available2025-08-21T15:26:29Z-
Data de envio: dc.date.issued2023-03-01-
Data de envio: dc.date.issued2023-03-01-
Data de envio: dc.date.issued2022-11-04-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.ejmech.2022.114640-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/241502-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/241502-
Descrição: dc.descriptionNanobiotechnology is a relatively unexplored area that has, nevertheless, shown relevant results in the fight against some diseases. Antimicrobial peptides (AMPs) are biomacromolecules with potential activity against multi/extensively drug-resistant bacteria, with a lower risk of generating bacterial resistance. They can be considered an excellent biotechnological alternative to conventional drugs. However, the application of several AMPs to biological systems is hampered by their poor stability and lifetime, inactivating them completely. Therefore, nanotechnology plays an important role in the development of new AMP-based drugs, protecting and carrying the bioactive to the target. This is the first review article on the different reported nanosystems using AMPs against bacteria listed on the WHO priority list. The current shortage of information implies a nanobiotechnological potential to obtain new drugs or repurpose drugs based on the AMP-drug synergistic effect.-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Pharmaceutical Sciences Tuberculosis Research Laboratory, Araraquara-
Descrição: dc.descriptionUniversidad Católica de Santa María Vicerrectorado de Investigación Facultad de Ciencias Farmacéuticas Bioquímicas y Biotecnológicas-
Descrição: dc.descriptionLaboratory of Nanobiotechnology Department of Genetics and Morphology Institute of Biological Sciences University of Brasilia-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Pharmaceutical Sciences Department of Drugs and Medicines, Araraquara-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Sciences and Engineering, Tupã-
Descrição: dc.descriptionSão Paulo State University (UNESP) Institute of Chemistry, Araraquara-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Pharmaceutical Sciences Tuberculosis Research Laboratory, Araraquara-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Pharmaceutical Sciences Department of Drugs and Medicines, Araraquara-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Sciences and Engineering, Tupã-
Descrição: dc.descriptionSão Paulo State University (UNESP) Institute of Chemistry, Araraquara-
Descrição: dc.descriptionFAPESP: 2018/25707-3-
Descrição: dc.descriptionFAPESP: 2020/13497-4-
Descrição: dc.descriptionFAPESP: 2020/16573-3-
Descrição: dc.descriptionFAPESP: 2021/14603-5-
Descrição: dc.descriptionCNPq: 404181/2019-8-
Descrição: dc.descriptionCNPq: 429139/2018-7-
Idioma: dc.languageen-
Relação: dc.relationEuropean Journal of Medicinal Chemistry-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAMP-
Palavras-chave: dc.subjectCarbapenem-resistant-
Palavras-chave: dc.subjectCephalosporin-resistant-
Palavras-chave: dc.subjectFluoroquinolone-resistant-
Palavras-chave: dc.subjectNanosystems-
Palavras-chave: dc.subjectNanotechnology-
Título: dc.titlePharmaceutical nanotechnology: Antimicrobial peptides as potential new drugs against WHO list of critical, high, and medium priority bacteria-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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