Influence of violet LED associated or not with peroxide gel on inflammation, mineralization, and collagen fiber maturation in dentin and pulp tissue

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade Federal de Minas Gerais (UFMG)-
Autor(es): dc.creatorda Silva, Livia Maria Alves Valentim-
Autor(es): dc.creatorCintra, Luciano Tavares Angelo-
Autor(es): dc.creatorde Alcântara, Sibele-
Autor(es): dc.creatorMachado, Nathália Evelyn da Silva-
Autor(es): dc.creatorBenetti, Francine-
Autor(es): dc.creatorErvolino, Edilson-
Autor(es): dc.creatorBriso, André Luiz Fraga-
Data de aceite: dc.date.accessioned2025-08-21T20:16:22Z-
Data de disponibilização: dc.date.available2025-08-21T20:16:22Z-
Data de envio: dc.date.issued2023-03-01-
Data de envio: dc.date.issued2023-03-01-
Data de envio: dc.date.issued2022-09-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.pdpdt.2022.102959-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/241385-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/241385-
Descrição: dc.descriptionObjectives: To evaluate the influence of violet LED, associated or not with a 17.5% hydrogen peroxide (HP) bleaching gel, on inflammation, mineralization in pulp tissue, and collagen fiber maturation in dentin and pulp tissue. Materials and methods: The maxillary molars of eighty Wistar rats were distributed into four groups (n = 10): CONT – without treatment; HP – 30 min application of 17.5% HP; LED – 20 min application of violet LED; and HP+LED – application of PH and violet LED. Rats were euthanized and jaws were processed for histologic and immunohistochemical evaluation (IL-17, IL-23, and osteocalcin) and picrosirius red immediately after (T0), and at 7 (T1), 15 (T2), and 30 days (T3) post-treatment, with Wilcoxon, Mann-Whitney, paired T-test, and T-test (α = 0.05). Results: HP and HP+LED presented necrosis and severe inflammatory infiltrate. When compared to CONT group, LED presented severe osteocalcin (OCN) immunostaining in T2 and less immature fibers in T2 and T3. Conclusion: The violet LED caused no severe damage to the pulp tissue, increased IL-17 and IL-23 expression in T0 when associated with HP, and had no influence on pulp tissue mineralization, besides accelerating the maturation of collagen fibers of dentin. Clinical relevance: Violet LED therapy induced no inflammation in the pulp tissue of rats and played no role in pulp tissue fibrosis, besides accelerating the maturation of dentin collagen fibers.-
Descrição: dc.descriptionDepartment of Preventive and Restorative Dentistry São Paulo State University (UNESP) School of Dentistry Araçatuba, José Bonifácio, Vila Mendonça, Araçatuba-
Descrição: dc.descriptionDepartment of Restorative Dentistry School of Dentistry Federal University of Minas Gerais (UFMG), Minas Gerais-
Descrição: dc.descriptionDepartment of Basic Sciences São Paulo State University (UNESP) School of Dentistry Araçatuba-
Descrição: dc.descriptionDepartment of Preventive and Restorative Dentistry São Paulo State University (UNESP) School of Dentistry Araçatuba, José Bonifácio, Vila Mendonça, Araçatuba-
Descrição: dc.descriptionDepartment of Basic Sciences São Paulo State University (UNESP) School of Dentistry Araçatuba-
Idioma: dc.languageen-
Relação: dc.relationPhotodiagnosis and Photodynamic Therapy-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBleaching-
Palavras-chave: dc.subjectCollagen-
Palavras-chave: dc.subjectInflammation-
Palavras-chave: dc.subjectViolet LED-
Título: dc.titleInfluence of violet LED associated or not with peroxide gel on inflammation, mineralization, and collagen fiber maturation in dentin and pulp tissue-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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