Mastoparans: A Group of Multifunctional α-Helical Peptides With Promising Therapeutic Properties

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversity of Brasília-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorde Santana, Carlos José Correia-
Autor(es): dc.creatorPires Júnior, Osmindo Rodrigues-
Autor(es): dc.creatorFontes, Wagner-
Autor(es): dc.creatorPalma, Mário Sérgio-
Autor(es): dc.creatorCastro, Mariana S.-
Data de aceite: dc.date.accessioned2025-08-21T17:24:18Z-
Data de disponibilização: dc.date.available2025-08-21T17:24:18Z-
Data de envio: dc.date.issued2023-03-01-
Data de envio: dc.date.issued2023-03-01-
Data de envio: dc.date.issued2022-06-24-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3389/fmolb.2022.824989-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/241326-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/241326-
Descrição: dc.descriptionBiologically active peptides have been attracting increasing attention, whether to improve the understanding of their mechanisms of action or in the search for new therapeutic drugs. Wasp venoms have been explored as a remarkable source for these molecules. In this review, the main findings on the group of wasp linear cationic α-helical peptides called mastoparans were discussed. These compounds have a wide variety of biological effects, including mast cell degranulation, activation of protein G, phospholipase A2, C, and D activation, serotonin and insulin release, and antimicrobial, hemolytic, and anticancer activities, which could lead to the development of new therapeutic agents.-
Descrição: dc.descriptionLaboratory of Toxinology Department of Physiological Sciences Institute of Biological Sciences University of Brasília-
Descrição: dc.descriptionLaboratory of Protein Chemistry and Biochemistry Department of Cell Biology Institute of Biological Sciences University of Brasília-
Descrição: dc.descriptionDepartment of Basic and Applied Biology Institute of Biosciences of Rio Claro São Paulo State University UNESP-
Descrição: dc.descriptionDepartment of Basic and Applied Biology Institute of Biosciences of Rio Claro São Paulo State University UNESP-
Idioma: dc.languageen-
Relação: dc.relationFrontiers in Molecular Biosciences-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectantimicrobial peptide-
Palavras-chave: dc.subjectlinear cationic α-helical peptide-
Palavras-chave: dc.subjectmast cell degranulation-
Palavras-chave: dc.subjectmastoparans-
Palavras-chave: dc.subjectsocial and solitary wasps-
Palavras-chave: dc.subjectvenom-
Título: dc.titleMastoparans: A Group of Multifunctional α-Helical Peptides With Promising Therapeutic Properties-
Tipo de arquivo: dc.typevídeo-
Aparece nas coleções:Repositório Institucional - Unesp

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