Natural product-based nanomedicine applied to fungal infection treatment: A review of the last 4 years

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversity of Araraquara (UNIARA)-
Autor(es): dc.creatorMarena, Gabriel Davi-
Autor(es): dc.creatorRamos, Matheus Aparecido dos Santos-
Autor(es): dc.creatorCarvalho, Gabriela Corrêa-
Autor(es): dc.creatorJunior, José Alberto Paris-
Autor(es): dc.creatorResende, Flávia Aparecida-
Autor(es): dc.creatorCorrêa, Ione-
Autor(es): dc.creatorOno, Gabriela Yuki Bressanim-
Autor(es): dc.creatorSousa Araujo, Victor Hugo-
Autor(es): dc.creatorde Camargo, Bruna Almeida Furquim-
Autor(es): dc.creatorBauab, Tais Maria-
Autor(es): dc.creatorChorilli, Marlus-
Data de aceite: dc.date.accessioned2025-08-21T16:54:28Z-
Data de disponibilização: dc.date.available2025-08-21T16:54:28Z-
Data de envio: dc.date.issued2023-03-01-
Data de envio: dc.date.issued2023-03-01-
Data de envio: dc.date.issued2022-07-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1002/ptr.7460-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/241317-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/241317-
Descrição: dc.descriptionFungal infections are one of the main public health problems, especially in immunocompromised patients, nosocomial environments, patients with chronic diseases, and transplant recipients. These diseases are increasingly frequent and lethal because the microorganism has a high capacity to acquire resistance to available therapy. The main resistance factors are the emergence of new strains and the uncontrolled use of antifungals. It is, therefore, important to develop new methods that contribute to combating fungal diseases in the clinical area. Natural products have considerable potential for the development of new drugs with antifungal activity, mainly due to their biocompatibility and low toxic effect. This promising antimicrobial activity of natural products is mainly due to the presence of flavonoids, terpenes, and quinones, which explains their antifungal potential. Pharmaceutical nanotechnology has been explored to enhance the delivery, selectivity, and clinical efficacy of these products. Nanotechnological systems provide a safe and selective environment for various substances, such as natural products, improving antifungal activity. However, further safety experiments (in vivo or clinical trials) need to be carried out to prove the therapeutic action of natural products, since they may have undesirable, toxic, and mutagenic effects. Therefore, this review article addresses the main nanotechnological methods using natural products for effective future treatment against the main fungal diseases.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionDepartment of Drugs and Medicines School of Pharmaceutical Sciences São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Biological Sciences School of Pharmaceutical Sciences São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Biological Sciences and Health University of Araraquara (UNIARA)-
Descrição: dc.descriptionDepartment of Nursing School of Medicine São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Drugs and Medicines School of Pharmaceutical Sciences São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Biological Sciences School of Pharmaceutical Sciences São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Nursing School of Medicine São Paulo State University (UNESP)-
Descrição: dc.descriptionFAPESP: 2014/50928-2-
Descrição: dc.descriptionFAPESP: 2018/23442-2-
Descrição: dc.descriptionFAPESP: 2019/09831-9-
Descrição: dc.descriptionCNPq: 465687/2014-8-
Formato: dc.format2710-2745-
Idioma: dc.languageen-
Relação: dc.relationPhytotherapy Research-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectfungal infection-
Palavras-chave: dc.subjectnanotechnology-
Palavras-chave: dc.subjectnatural products-
Palavras-chave: dc.subjectresistance-
Palavras-chave: dc.subjecttreatment-
Título: dc.titleNatural product-based nanomedicine applied to fungal infection treatment: A review of the last 4 years-
Tipo de arquivo: dc.typevídeo-
Aparece nas coleções:Repositório Institucional - Unesp

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